Pregnancy may physiologically trigger pregnant women's cardio-vascular system to progressively adapt with significant structural and functional changes, such as increasing blood volume, cardiac output, heart rate and stroke volume as well as decreasing blood pressure and systemic vascular resistance, including hypertension which is possibly triggered by family history of hypertension. The Cold Pressor Test (CPT) was conducted to see pregnant women's blood pressure reactivity differences with and without family history of hypertension. This research aims at examining pregnant women's blood pressure reactivity differences with and without family history of hypertension after undergoing the Cold Pressor Test (CPT). This quasi-experimental research measured both systolic and diastolic blood pressure changes before and after undergoing the Cold Pressor Test (CPT), while the data was processed using Mann-Whitney test. Results: Of 80 pregnant women's mean systolic blood pressure with family history of hypertension before and after undergoing the Cold Pressor Test (CPT)was respectively 103.82 mmhg and 126.76 mmhg, while, their mean diastolic blood pressure before and after undergoing the Cold Pressor Test (CPT) was respectively 76.62 mmhg and 100.29 mmhg. The pregnant women's mean systolic blood pressure without family history of hypertension before and after undergoing the Cold Pressor Test (CPT) was 107.91 mmHg and 118.87 mmHg while their mean diastolic blood pressure before and after undergoing the Cold Pressor Test (CPT) was respectively 76.62 mmHg and 78.50 mmHg. After the data was processed using Mann-Whitney test it showed a significance value of0.003. Because the p-value was <0.05, it can be concluded that there was a significant difference between pregnant mothers with and without family history of hypertension and those with both systolic hypo-reactor and hyper-reactor. Conclusion: there is a significant difference between pregnant women with and without family history of hypertension and blood pressure.
Kulit Pisang Hijau Lumut (Musa x paradisiaca L.) merupakan limbah organik yang masih belum banyak dimanfaatkan. Penelitian ini bertujuan untuk menentukan Konsentrasi Hambat Minimum (KHM) dan Konsentrasi Bunuh Minimum (KBM) ekstrak metanol Kulit Pisang Hijau Lumut terhadap bakteri Staphylococcus aureus dan Escherichia coli, serta mengetahui golongan senyawa metabolit sekundernya. Ekstraksi dilakukan dengan metode maserasi, uji aktivitas antibakteri dilakukan dengan metode sumur difusi agar, dan skrining fitokimia dilakukan dengan menggunakan pereaksi pendeteksi wagner dan mayer untuk alkaloid, pereaksi Lieberman-Burchard untuk steroid/terpenoid, MgHCl untuk flavonoid, FeCl3 untuk fenol, dan HCl untuk saponin. Maserasi 1kg kulit pisang hijau menghasilkan ekstrak kental metanol sebanyak 83,45 gram. Hasil uji aktivitas antibakteri menunjukkan bahwa ekstrak metanol memiliki nilai KHM sebesar 8% dan KBM sebesar 10% terhadap bakteri S. aureus dan KHM sebesar 10% serta KBM sebesar 20% terhadap bakteri E.coli. Skrining fitokimia menunjukkan hasil positif terhadap alkaloid, fenol, flavonoid dan terpenoid. Kata kunci: antibakteri, Escherichia coli, kulit pisang, Staphylococcus aureus, uji fitokimia. Hijau lumut banana peels (Musa x paradisiaca L.) are organic waste that is still not widely used. This study aimed to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of methanol extract against Staphylococcus aureus and Escherichia coli as well as the secondary metabolite compounds. Extractions were done by maceration methods, antibacterial activity assay was carried out by agar well diffusion method, and phytochemical screening was performed using secondary metabolite detection reagents such as alkaloids, flavonoids, steroids/terpenoids, phenols, and saponins. Maceration of 1kg of the banana peels produced 83.45 grams of crude methanol extract. The activity assays of methanol extract indicated that the MIC and MBC against S.aureus was 8% and 10%, while against E. coli was 10% and 20%, respectively. The result of phytochemical screening showed that the banana peels were positive for alkaloids, fenols, flavonoids dan terpenoids. Keywords : antibacterial, Escherichia coli, hijau lumut banana peels, phytochemically test, Staphylococcus aureus.
As 60% of maternal deaths occurred during childbirth, 26.32% occurred during pregnancy and 13.68% occurred at the time of delivery. The causes of maternal mortality include metabolic disorders was 0.87%, infections of 4.34%, circulatory system disorders, 12.36%, bleeding 30.37%, hypertension in pregnancy 32, 97% and others 19, 09%. Cold Pressor Test is one of the tests that can be used to screen for the tendency of hypertension. The purpose of this study is to explore the risk of hypertension in pregnancy by administering a cold pressor test (CPT). This research is a case-control study or analytic survey with a retrospective approach. This research was conducted at Kembaran Puskesmas 1 (Commubity Health Center) with a population of all pregnant women and the sample size in this study was calculated using the case-control research design formula and obtained a sample of 40 for the case group and 40 respondents for the control group. Data were analyzed by using Pearson ChiSquare. The result showed that most pregnant women undergoing cold pressor tests are categorized as type reactors or have a risk of developing pregnancy hypertension. Meanwhile, the results of screening in pregnant women whose cold pressor test showed hyperactivity, had 23,619 times the risk of pregnancy hypertension. The conclusion was that CPT examination can be used as a reference to predict hypertension in pregnancy.
Latar Belakang: Abortus pada kehamilan akan mengakibatkan pengaruh yang buruk pada ibu diantaranya adalah perdarahan, perforasi uterus terutama pada uterus dalam posisi hiperretofleksi, syok hemoragik, infeksi dan juga kematian pada ibu. Untuk mengurangi efek yang ditimbulkan dari terjadinya abortus pada ibu, maka perlu mengetahui faktor-faktor yang mempengaruhi abortus sehingga sedini mungkin dapat dicegah atau diberikan asuhan yang tepatTujuan: Penelitian ini untuk mengetahui faktor determinan (usia, gravida, umur kehamilan, paritas dan jarak kehamilan) dengan terjadinya abortus pada ibu hamilMetode: Penelitian ini merupakan penelitian deskriptif analitik dengan desain case control. Penelitian dilakukan di RSUD Goeteng Tarunadibrata Purbalingga. Populasi dalam penelitian ini adalah seluruh ibu yang mengalami abortus dan tidak mengalami abortus di di RSUD Goeteng Tarunadibrata Purbalingga dengan jumlah sampel sebanyak 50 untuk kelompok kasus dan 50 untuk kelompok kontrol. Data kejadian abortus, usia, gravida, umur kehamilan, paritas dan jarak kehamilan diambil dari rekam medis pasien dan di analysis dengan menggunakan analisis point biserial dan regresi logistic berganda.Hasil: Ada hubungan yang signifikan antara usia ibu dengan kejadian abortus (p<0.01; r=0.297). Ada hubungan yang signifikan antara gravida dengan kejadian abortus (p<0.01; r=-0.272). Ada hubungan yang signifikan antara umur kehamilan dengan kejadian abortus (p<0.05; r=-0.224). Ada hubungan yang signifikan antara paritas dengan kejadian abortus (p<0.05; r=-0.252). Ada hubungan yang signifikan antara jarak kehamilan dengan kejadian abortus (p<0.05; r=-0.224). Usia ibu, gravida, umur kehamilan, paritas dan jarak kehamilan secara bersama-sama mempengaruhi terjadinya abortus pada ibu hamil (F=38.244, p<0.01; R2=0.574). Umur kehamilan merupakan faktor yang paling menentukan dalam terjadinya abortus pada ibu hamil (t= -13.093; p<0.01; partial correlation= -0.751)Kesimpulan: Usia ibu, gravida, umur kehamilan, paritas dan jarak kehamilan secara bersama-sama mempengaruhi terjadinya abortus pada ibu hamil, namun usia kehamilan merupakan faktor yang paling singnifikan dalam terjadinya abortus pada ibu hamil.
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