Thymic stromal lymphopoietin (TSLP) is known to be associated with allergic diseases. It is also suggested that TSLP has a role in autoimmune diseases such as psoriasis; however, the associated pathways remain unknown. There is currently little information on TSLP in psoriasis vulgaris. We investigated TSLP expressions on lesional and non-lesional skin of psoriasis vulgaris patients using reverse transcription- polymerase chain reaction. TSLP level was also investigated in serum from psoriasis vulgaris patients compared to healthy control using enzyme-linked immunosorbent assay. TSLP expression was higher in lesional skin (1.90) compared to non-lesional skin (1.76); however, the difference was not statistically significant (P>0.05). TSLP serum levels were significantly higher in psoriasis patients (287.40 pg/dL) as compared to controls (114.70 pg/dL) (P<0.05). This study concluded that TSLP levels in the serum of psoriasis vulgaris patients are higher than controls. TSLP was also found in keratinocyte of psoriasis patients, the expression was higher in the lesional compared to non-lesional skin; however, this difference is statistically insignificant. These findings suggest that TSLP may play a role in the pathogenesis of psoriasis vulgaris, but its exact role remains unclear.
Bullous pemphigoid (BP) and psoriasis are chronic recurrent inflammatory skin diseases. The pathogenesis of concurrence of BP with psoriasis is still unknown. A 39-year-old male with a five-year history of chronic plaque psoriasis developed itchy large tense bullae on the trunk and upper extremities after he had been receiving narrow band ultraviolet B (NBUVB) therapy over five months. Skin biopsy from bulla on the trunk showed typical histological features of BP. Direct immunofluorescent staining showed deposit of immunoglobulin G and C3 in the basement membrane zone (BMZ) which supported the diagnosis of BP. It has been postulated that the autoimmune process responsible for BP lesions might be induced by ultraviolet light therapy and/or the inflammatory processes that occur in psoriasis.
ABSTRAKTujuan penelitian ini untuk menganalisis optimalisasi penerimaan keluarga petani dengan rasio skala usaha yang paling ideal pada integrasi usahaternak sapi Pasundan dengan usahatani padi dan faktor produksi yang memberikan daya ungkit terhadap penerimaan keluarga. Responden adalah petani peternak yang melakukan integrasi usahaternak dengan usahatani padi, berjumlah 94 keluarga. Metoda penelitian adalah survey, di empat kabupaten sentra produksi sapi pasundan yang ditentukan secara purposif. Data dianalisis dengan linear programming dan fungsi produksi Cobb Douglass. Hasil analisis: (1) max Z = -(4,584,841x 1 +1574260 (x 2 +x 3 )) + (6,000,000jx 1 +4000000 (j x 2 +j x 3 )), persamaan ini dibatasi fungsi kendala, yaitu; tenaga kerja, transfer produk antara padi dan ternak, transfer pupuk, modal usaha musim tanam-I dan musim tanam-II. (2) Y integrasi = 15721319,75 -72,541 lahan -1,317 pupuk + 4,667 bibit + 487.765,94 tenaga kerja usahatani + 6.339.170,199 nilai ternak -935,559 pakan + 162.618.999 tenaga kerja usaha ternak. Kesimpulan pertama, penerimaan keluarga yang optimal pada integrasi usaha ternak sapi pasundan dan padi per tahun berasal dari rasio skala usaha ternak 6,02 UT dan skala usahatani 0,5 hektar. Kedua, penerimaan integrasi usahatani ternak dapat diterangkan oleh kombinasi variabel faktor produksi luas lahan, tenaga kerja usahatani dan ternak, bibit usahatani, pakan, dan modal (ternak awal) sebesar R 2 = 87,66%. Ketiga, variabel modal ternak awal berdaya ungkit terhadap penerimaan keluarga sebesar 81,52%.Kata Kunci: integrasi sapi-padi, sapi pasundan, penerimaan keluarga. ABSTRACTThis research aimed to analyze the revenue optimization of farmer family with ratio of the most ide al farm scale in the integration of Pasundan cattle and paddy farm, and to analyze the most leveraging pr oduction factor towards the family revenue. The respondents were 94 farmers who had integrated farming between cattle and paddy. This research used survey method in four regions purposively based o n Pasundan cattle centre. Data were analyzed with linear programming and production function of Cobb Douglass. The results were: (1) max Z = -(4,584,841x 1 +1574260 (x 2 +x 3 )) + (6,000,000jx 1 +4000000 (j x 2 +j x 3 )); this function consist of constraints: labour, transfer products between cattle and paddy farm, transfer fertilizer, capital of paddy farming in planting season-I and season-II. (2) Y integration = 15,721,319.75 -72.541 land -1.317 fertilizer + 4.667 seeds + 487765.94 farming labour + 6339170.199 cattle value -935.559 feed + 162618.999 cattle labour. There were some conclusions: Firs t, the integration of Pasundan cattle and paddy farming produced the optimum family revenue/year, with ratio of 6.02 animal unit and 0.5 ha of paddy farming; Second, the production factor of agricultural land, labour, seeds, feed and capital (cattle) were explained (R 2 =87.66%) toward the integration revenue; 270
Ternak Ayam Pelung saat ini merupakan salah satu modal bangsa dalam mempertahankan sumberdaya genetik ternak nasional. Minat konsumen dan gairah petani semakin meningkat sementara usahaternak tidak cukup kuat untuk menutup kebutuhan tersebut. Usaha Ayam Pelung memerlukan solusi kreatif berdasarkan potensinya. Tujuan dari penelitian ini adalah untuk mengidentifikasi dan merumuskan strategi yang dapat dibuat oleh stakeholder terkait; serta memilih strategi alternatif terbaik. Metode penelitian adalah studi kasus dengan menggunakan informan sebagai sumber data primer. Model analisis yang digunakan adalah analisis SWOT dan QSPM. Berdasarkan diagram kartesius maka strategi WO adalah strategi yang sesuai dengan kondisi usaha Ayam Pelung di Kabupaten Cianjur. Berdasarkan faktor-faktor internal dan eksternal strategi yang dapat dirumuskan dari faktor internal dan eksternal adalah: (1) membuat kebijakan pemerintah dan breeding centre Ayam Pelung, (2) penyerapan CSR yang difasilitasi oleh perguruan tinggi dan dinas peternakan, dan (3) pelatihan pembuatan dimsum sebagai olahan Ayam Pelung serta pembinaan pengadaan pakan mandiri. Seluruh strategi layak untuk diupayakan namun urutan prioritas yang dapat membantu keberlanjutan usaha ayam pelung di Kabupaten Cianjur adalah strategi yang pertama, ketiga, dan kedua.
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