Injection of M dopamine or M dibutyryl cyclic AMP (dbcAMP) into intact Carcznus maenas significantly increased influx of sodium from 100% sea water. Injection of pericardial organ (PO) extract, which contains dopamine, also increased influx of sodium. Animals injected with dopamine or PO extract and gills treated with dbcAMP in vitro showed increased NaiK-ATPase activity in the microsomal fraction of the gills. These results suggest a mechanism for short-term activation of Na/K-ATPase when crabs are transferred to a dilute medium.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.