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Local traditional knowledge of the use of antimalarials is still widespread in indigenous communities of the Upper Rio Negro, where 46 plants species used against malaria were recorded. Our studies highlight promising new plants for future studies: Glycidendron amazonicum, Heteropsis tenuispadix, Monopteryx uaucu, Phenakospermum guianensis, Pouteria ucuqui, Sagotia brachysepala and notably Aspidosperma schultesii, Ampelozizyphus amazonicus, Euterpe catinga, E. precatoria, Physalis angulata, Cocos nucifera and Swartzia argentea with high-use consensus. Experimental validation of these remedies may help in developing new drugs for malaria.

ResumoO presente estudo teve por objetivo levantar o conhecimento a respeito de plantas medicinais dos moradores da área urbana central do município de Bandeirantes-PR. Os dados foram coletados no período de fevereiro a dezembro de 2003, através de entrevistas feitas com mulheres, com idade acima de 40 anos, selecionadas pelo seu conhecimento sobre o uso medicinal de espécies vegetais. As entrevistas foram realizadas através de formulários pré-estruturados, com questões referentes ao entrevistado e à planta citada. Cada entrevista foi registrada com o auxílio de gravador e fotografias para evitar perdas de informações. Foram coletadas amostras vegetais para montagem de exsicatas para posterior identificação botânica. Após a identificação, as exsicatas foram incorporadas ao herbário do Jardim Botânico da Faculdades Luiz Meneghel -FALM, Bandeirantes, PR. Foram registradas 31 espécies vegetais distribuídas em 19 famílias, sendo a Lamiaceae com maior número de espécies, seguida por Rosaceae, Asteraceae e Euphorbiaceae. A parte vegetal mais utilizada na preparação dos remédios foi a folha, e a forma de preparo mais comum foi a infusão. As indicações terapêuticas mais citadas nas entrevistas foram dor de cabeça, diarréia, febre, cólica e infecção. AbstractThe present study had the objective of collecting data about herbal remedies from residents of the central urban area fron the city of Bandeirantes, Paraná. The data were collected from February to December 2003, through interviews done with people aging over 40 years old, chosen considering the knowledge about the medical use of herbal species, based on indication done by local residents. The interviews were kept using a form with questions related to the interviewed one and to the herbal medicine mentioned. Each interview was recorded using a cassette recorder and pictures for a later transcription. Vegetal samples were collected as often as possible and the samples were herborized, then exsicats were prepared for later botanical identification. After the identifications, the exsicats were incorporated to the herbaceous border of FALM Botanical Garden (Faculdades Luiz Meneghel, Bandeirantes, Paraná). 31 plants (herbal remedies) were indicated, distributed among 19 families. The Lamiaceae contributed with the highest number of species, followed by Rosacea, Asteraceae and Euphorbiaceae. Leafs were the most used part for the medical preparation and the most common way of preparation was the infusion. The most mentioned therapeutic indications were: headaches, stomachahes, fever, stomach cramps and infection.

Clove basil (Ocimum gratissimum) extracts were obtained with supercritical CO2. Clove basil was cultivated using 0, 4, 8 and 12 kg/m2 of organic fertilizer and was harvested in four seasons: winter, spring, summer and autumn, in the Southern Hemisphere. The extracts' global yields were determined at 40C and 150 bar for samples from all cultivation conditions and harvesting seasons. For selected samples, the extracts' global yields at 40C were determined for pressures of 100, 150, 200, 250 and 300 bar. The extracts were analyzed by gas chromatography–flame ionization detector. Antioxidant activity (AA) was assessed using the coupled reaction of β‐caroteneand linolenic acid. The extracts' global yields varied from 0.91 to 1.79% (dry basis), and the AAs varied from 62 to 84% compared with the control β‐carotene. Eugenol and β‐selinene were the major compounds. The relative proportion of eugenol varied from 35 to 60%, while the content of β‐selinene remained approximately constant (11.5–14.1%, area). The other substances quantified in the extracts were 1,8 cineole, trans‐caryophyllene and α‐selinene.

Pothomorphe umbellata (L.) Miquel, is a medicinal species that belong to the Piperaceae family and commonly called "pariparoba" and "caapeba". It grows in regions rich in humus, humidity and under the shade of trees, which contribute for its best growth as it is considered a species sciophyte. The effect of shade on the yield and chemical composition of essential oil of Pothomorphe umbellata (Piperaceae) leaves was evaluated. Nine-month-old seedlings were planted in October 2002 and subjected to three shade levels (30%, 50%, 70%) and full sun; the experimental design was in randomized blocks, with four treatments and six replications, in split-plot in time scheme. Two harvests of aerial part were made (05/2003 and 05/2004). Essential oil was extracted by hydrodistillation and chemically analyzed by gas chromatography-mass spectrometry (GC-MS). The highest essential oil yield was observed in the second harvest and plants under 30% shade. Twenty-six chemical substances were identified, of which trans-nerolidol was predominant. Key words: Piperaceae, cultivation systems, trans-nerolidol, medicinal plant Efeito de níveis de sombreamento no teor e composição química do óleo essencial de folhas de Pothomorphe umbellata (L.) MiquelRESUMO: Pothomorphe umbellata (L.) Miquel é uma espécie medicinal brasileira, pertencente à família Piperaceae e popularmente conhecida como pariparoba e capeba. Desenvolve-se em regiões ricas em húmus, umidade e abaixo das sombras de árvores, que contribuem para seu melhor desenvolvimento, é considerada uma espécie esciófita. Avaliou-se o efeito do sombreamento no teor e composição química do óleo essencial de folhas Pothomorphe umbellata (Piperaceae). Mudas com nove meses foram levadas para campo em outubro de 2002 e submetidas a três níveis de sombreamento (30%, 50%, 70%) e a pleno sol, em delineamento experimental de blocos ao acaso, com quatro tratamentos e seis repetições, no esquema de parcelas subdivididas no tempo. Foram realizadas duas colheitas da parte aérea