Mamanwa indigenous people (IP) mostly lived in Caraga region, Philippines. Most of them depended on the traditional method of herbal plants for medication. This study aims to determine the bioactive compounds present in the fifteen ethnomedicinal plants extract through IR spectrophotometric analysis for the presence of the different functional group in the plant extract. The presence of the peaks forms IR spectroscopy for the stretching of O-H/ N-H, C-H, CO and C-Cl /C-S, S-H, N=O and C=O for the functional groups alcohols, carboxylic acids, alkanes, alkenes, halogens, amide, aromatic compounds, ethers, amino acids, lactones, nitro compounds, acid anhydrides and aldehydes that makes this possible potential antibiotics and medicine.
The use of macroalgae as a substitute for synthetic drugs is gaining popularity. Macroalgae is a simple and fascinating species that is a treasure chest of natural chemicals and beneficial ingredients and can be found in some areas of the marine environment. This study was undertaken to evaluate the toxicity effect through brine shrimp bioassay and presence of the secondary metabolites through phytochemical screening of ethanolic extract in selected macroalgae collected along the intertidal zone in selected areas of the Barangays in Loreto Dinagat Islands. A total of ten macroalgae were collected containing two samples for red algae, four samples for green algae and four samples brown algae. Screening of phytochemical constituents showed positive results for flavonoids, anthraquinones, saponins, tannins, steroids and alkaloids. The toxicity levels of each selected macroalgae were dosedependent. Three of the samples of macroalgae were identified as highly toxic, and seven of the selected macroalgae were identified as moderately toxic. The result of the present study confirmed that some of the macroalgae present in Loreto Dinagat Islands were rich sources of phytoconstituents which can be isolated and further screened for various biological activities. This study also supports the use of the macroalgae in the treatment of diseases in traditional medicine and also recommends the physico-chemical characterization and further biological evaluation of the macroalgae.
The study was conducted to scientifically validate 15 herbal plants traditionally utilized by the Mamanwa of Mindanao for child health care. Phytochemical screening for alkaloids, anthraquinones, flavonoids, saponins, steroids and tannins was done as well as antimicrobial activity testingof thecrude ethanolic and methanolic extracts against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa. Result of Phytochemical analysis showed the presence of anthraquinones in the 14 plants sample except alibangbang leaves, 13 were present with alkaloid and steroid except tagbak tubers and togup bark, 9 plant sample contains flavonoids, 5 plant sample contains saponins and 4 plant sample contains tannins. Antimicrobial result from ethanolic and methanolic extract shows only three herbal plants were found to be inactive with the four test organisms and the rest of the test plants were partially active, active and very active. Alibangbang leaves with ethanolic and methanolic extract showed high affinity or very active with S. aureus, P. aeruginosa and E. coli while lunas bark in ethanolic extract was found to be very active with S. aureus and togup bark in ethanolic extract showed very active with P. aeruginosa.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.