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The region of Apulia, which is located in the south-east tip of the Italian Peninsula, has a typical Mediterranean climate with mild winters and hot-dry summers. Agriculture, an important sector of its economy, is potentially threatened by future climate change. This study describes the evolution of seasonal temperature and precipitation from the recent past to the next decades and estimates future potential impacts of climate change on three main agricultural products: wine, wheat and olives. Analysis is based on instrumental data, on an ensemble of climate projections and on a linear regression model linking these three agricultural products to seasonal values of temperature and precipitation. In Apulia, precipitation and temperature time series show trends toward warmer and marginally drier conditions during the whole analyzed (1951–2005) period: 0.18 °C/decade in mean annual minimum temperature and −14.9 mm/decade in the annual total precipitation. Temperature trends have been progressively increasing and rates of change have become noticeably more intense during the last 25 years of the twentieth century. Model simulations are consistent with observed trends for the period 1951–2000 and show a large acceleration of the warming rate in the period 2001–2050 with respect to the period 1951–2000. Further, in the period 2001–2050, simulations show a decrease in precipitation, which was not present in the previous 50 years. Wine production, wheat and olive harvest records show large inter-annual variability with statistically significant links to seasonal temperature and precipitation, whose strength, however, strongly depends on the considered variables. Linear regression analysis shows that seasonal temperature and precipitation variability explains a small, but not negligible, fraction of the inter-annual variability of these crops (40, 18, 9 % for wine, olives and wheat, respectively). Results (which consider no adaptation of crops and no fertilization effect of CO2) suggest that evolution of these seasonal climate variables in the first half of the twenty-first century could decrease all considered variables. The most affected is wine production (−20 ÷ −26 %). The effect is relevant also on harvested olives (−8 ÷ −19 %) and negligible on harvested wheat (−4 ÷ −1 %)

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