This cross-sectional study documents the demographic features of asthmatics seeking acute asthma care at four institutions on the island of Trinidad from January 1 to December 31, 1997. More than 15,000 (15,035) different patients made 27,353 visits during the study period. Pediatric and adolescent male patients outnumbered females, but this was reversed in patients aged 20-69 years. Frequency of visits per patient ranged from 1 to 242. Significant variation in monthly admissions was observed; admission rates were highest in the last quarter of the year but were lowest in July and August. The overall crude prevalence rate was estimated at 1.71 per 100 (range 1.16-2.34).
e13079 Background: The recent epidemiology of cancers in Haiti is poorly understood, since there is no functional national cancer registry. The data from GLOBOCAN 2012 and 2018 are estimations that do not reflect the actual cancer burden in Haiti. The aim of this study was to present the three-year epidemiology of cancer cases managed by a cancer program in Port-au-Prince, Haiti. Methods: A retrospective study was conducted on patients aged 15 years old or more with pathological and/or clinical diagnosis at the cancer clinic of Innovating Health International (IHI) from January 2016 to December 2018. The chart review collected variables such as age, gender, date of diagnosis, cancer type and outcome to present this epidemiological profile of cancers. Results: One thousand four hundred and eighty-one (1481) cancer cases were managed during this study period, respectively 282 in 2016, 513 in 2017 and 686 in 2018 (p < 0.001). 84% of the patients were female and 16% male. The mean age of the study population was 51.8 years [15 –92], ranging from 51.7 years in 2016 to 52.1 years in 2018 (p = 0.56). Adolescents and young adults (15-39 years old) represented 20.9% of this cohort and geriatric cases (≥ 65 years old) 19.6%. Breast cancer was the most common type (n = 686, 46.3%), followed by gynecological cancers (n = 330, 22.3%) with cervical cancer representing 70.9% of the cases, gastrointestinal cancers (n = 138, 9.3%), hematological malignancies (n = 75, 5.1%), head and neck cancers (n = 64, 4.3%), sarcomas (n = 40, 2.7%), urological cancers (n = 32, 2.2%), skin cancers including melanoma (n = 29, 2%), lung cancer (n = 13, 0.9%), thyroid cancer (n = 10, 0.7%) and central nervous system (CNS) cancers (n = 2, 0.1%). 4.2% of the patients (n = 62) had a cancer of unknown primary (CUP). Breast cancer was the most common type among women (54.7%) and gastrointestinal cancers the most diagnosed among men (25.3%). There was a predominance of women for most of the cancer types. The overall mortality rate was 31% and 8.6% of the patients were lost to follow-up. Conclusions: There was a significant increase of cancer cases in our cancer clinic from 2016 to 2018, likely due to a combination of our cancer awareness campaign, increased diagnosis and referral. Cancer mainly affects Haiti’s young, feminine and active population. Breast and cervical cancers were the most prevalent in this retrospective cohort. The under-representation of prostate and other urological cancers, lung cancer, acute leukemias and CNS cancers was likely due to underdiagnosis, misdiagnosis, under-referral or early mortality.
Conclusions: To our knowledge, this is one of the largest studies of young breast cancer patients in Africa comparing the local failure after mastectomy and BCS. In this large study, breast-conserving surgery was not detrimental to locoregional control in young African breast cancer patients and should be considered whenever feasible and discussed with patients for a joint decision.Legal entity responsible for the study: The authors.
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