oal: The research was undertaken with the aim to determine the frequency of positive findings of serological tests for celiac disease of the first relatives of children with celiac disease. Materials and methods: The study included 175 first relatives of 68 children suffering from celiac disease. Of that number, 75 (40 mothers and 26 fathers), 4 sisters and five brothers agreed to be tested for the presence of antibodies to celiac disease. For each subject were done tests on presence of anti-gliadin IgA, IgG antigliadin antibodies and IgA antibodies on tissue transglutaminase in the Poly
Aim: The aim of this research was to determine the association of recurrent abdominal pain and Helicobacter pylori (H. pylori) infection in childhood, in correlation with the finding of an upper endoscopy.Introduction: Recurrent abdominal pain (RAP) was defined according to Apley and Naish's criteria from the year 1959 as at least three or more episodes of abdominal pain lasting longer than three months in children older than 3 years, and severe enough to prevent normal activities in child. The association of RAP and H. pylori has been analyzed in several different researches, and there are conflicting results about their interconnection.However, the ethiological association of the presence of H. pylori with the onset and development of acute and chronic active gastritis and duodenal ulcer is known.Matrherial and method: The research protocol included a total of 77/183 (42.07%) children divided by age into three subgroups: preschool age (3 to 6.9 years), school age (7 to 10.9 years) and adolescent age (11 to 15 years) in whom the diagnosis of RAB was determined by meeting the criteria according to Apley and Naish (1959), and the American Academy of Pediatrics (2005). H. pylori infection was confirmed by enzyme-linked immunosorbent assay (ELISA), while esophagogastroduodenoscopy was performed by the device for upper endoscopy type Olimpus GIF Type Q156, in the endoscopic cabinet of the Clinic for Internal Medicine, University Clinical Center Tuzla.Results: Of the total number of examined children (77), the analyse of Helicobacter pylori infection presence showed the biggest number of positive findings in school age 91.3%, in adolescent age 78.0%, while the smallest number was in preschool age (25.0%). The most common findings of upper endoscopy and microscopic findings were described as: antritis acuta in 16%, gastritis chronica activa et erosiva in 32%, and duodenitis acuta (12%).Conclusion: A significant association of H. pylori infection and RAP are confirmed by positive finding of esophagogastroduodenoscopy, leading to conclusion that immunological testing for the presence of this bacteria is justified. After obtaining a positive finding with confirmed infecion, it is necessary to start with the treatment.
The aim of this study was to examine the results of endoscopic treatment for vesicoureteral reflux at our institution. Patients and Methods -The study was of prospective character and included 63 patients with diagnosed vesicoureteral reflux (VUR) in a total of 87 ureters. All patients underwent endoscopic treatment using the hydrodistension implantation technique (HIT) or the subureteral transurethral injection technique (STING). Patients were observed for recurrent UTI after treatment. Fifty (79.4%) patients had no recurrent UTI and 8 (12.7%) patients underwent a second endoscopic treatment and they are now free of UTI. One patient out of the 8 required a third injection. Results -The study included 63 patients with a total of 87 ureters, treated with Dx/HA copolymer. The mean age of the patients was 5.5 years (from 1 to 14 years). Fifty -one patients were female (80.1%) and 12 male (19.9%). Unilateral VUR was found in 39 and bilateral in 24 patients. Fifty-three patients (60.1%) were treated with a combination of HIT and STING procedures and 34 (39.9%) patients were treated with the STING procedure only. No more than 1 ml Dx/HA copolymer was injected into one ureteral orifice. No major complications were observed. Conclusion -The advantages of endoscopic treatment are short stay in hospital, no major complications and short operating time, in comparison to open surgery and it should be the first choice of treatment for patients with vesicoureteral reflux.
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