These results provide the basis for the ongoing use of the test, given that it is acceptable to miss some cases of malingering with such a screening test, but one does not want to have many false positives.
SPECT studies were carried out on three occasions in a woman with schizophrenia. Marked 'hypofrontality' was demonstrated during an acute phase of illness. A study during remission was within normal limits, but some return of the original defect was noted in a subsequent relapse. These findings parallel those found in PET studies of schizophrenia.
In The Nature of Disease I argued that a value-free account of our concept of disease cannot be given. Part of this argument consisted in showing that diseases as a class do not constitute a natural kind. To understand this, we need only see that we define and classify conditions into diseases and non-diseases not in terms of their causes but in terms of their effects. While no philosophical position is watertight, the arguments overwhelmingly favour the conclusion that diseases do not constitute a natural kind.
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