Objective. To determine the impact of a faculty-directed, residency interest group on the knowledge, confidence, and preparedness about residency-related topics of third-year (P3) and fourth-year (P4) pharmacy students. Design. Faculty members implemented residency interest group sessions on residency and career preparation for P3 and P4 students. Group meetings consisted of four 2-to 3-hour sessions that covered topics such as residency timeline and resources, letter of intent and CV development, proper interview techniques, and navigating the midyear clinical meeting. Residency directors throughout Mississippi, current pharmacy residents, P3 and P4 students, and other faculty members were invited to attend these sessions. Assessment. Surveys were administered prior to and after completion of the interest group sessions. Students who attended the sessions demonstrated increased knowledge, confidence, and preparedness on residency-related topics. However, non-attendees also demonstrated increased knowledge, confidence, and preparedness from baseline. Conclusion. The majority of students who accepted a residency position had attended at least 1 residency interest group session, suggesting this program had a positive influence.
Purpose
The purpose of this article is to educate nurse practitioners about the role of Toujeo®, insulin glargine U‐300 (Gla‐300), which is a new option for the treatment of diabetes mellitus.
Data sources
A comprehensive literature search was conducted using MEDLINE with the key terms: insulin glargine 300, Toujeo, Gla‐300, and EDITION for clinical trial data. Other resources included package inserts, drug information websites, and the World Health Organization (WHO).
Conclusions
Gla‐300 appears to be a safe and effective option for basal insulin therapy. In clinical trials, it was shown to be equally efficacious as Gla‐100 with fewer episodes of hypoglycemia and slightly less weight gain, and subjects receiving Gla‐300 required approximately 10 units more basal insulin to obtain the same hemoglobin A1c (HbA1c) as subjects receiving Gla‐100.
Implications for practice
This new basal therapy option represents a potential advantage for patients who require higher doses of insulin because of the higher concentration of Gla‐300. The lower incidence of hypoglycemia and more predictable pharmacokinetics could offer a significant therapeutic benefit in difficult‐to‐control patients with diabetes mellitus. The biggest disadvantage of this product is the slightly higher insulin dosage that is required to improve and/or maintain patients’ HbA1c.
Depending on the patient's needs, these newer agents may offer some advantages. Insulin glargine U300 and IDeg 200 are concentrated, allowing for administration of large doses by less volume, thereby theoretically improving absorption. For patients needing flexible dosing, IDeg may be beneficial. The ultra-long-acting agents may also be useful if it is suspected that the basal insulin is not lasting the entire day.
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