We investigate the shape and mechanical properties of liquid interfaces down to nanometer scale by atomic force microscopy (AFM) and scanning electron microscopy (SEM) combined with in situ micromanipulation techniques. In both cases, the interface is probed with a cylindrical nanofiber with radius R of the order of 25-100 nm. The effective spring constant of the nanomeniscus oscillated around its equilibrium position is determined by static and frequencymodulation (FM) AFM modes. In the case of an unbounded meniscus, we find that the effective spring constant k is proportional to the surface tension γ of the liquid through k = (0.51±0.06) γ, regardless of the excitation frequency from quasistatic up to 450 kHz. A model based on the equilibrium shape of the meniscus reproduces well the experimental data. Electron microscopy allowed to visualize the meniscus profile around the fiber with a lateral resolution of the order of 10 nm and confirmed its catenary shape. The influence of a lateral confinement of the interface is also investigated. We showed that the lateral extension L of the meniscus influences the effective spring constant following a logarithmic evolution k ~ 2πγ⁄ln(L/R) deduced from the model. This comprehensive study of liquid interface properties over more than four orders of magnitude in meniscus size, shows that advanced FM-AFM and SEM techniques are promising tools for the investigation of mechanical properties of liquids down to nanometer scale.2

We present a comprehensive study of the capillary force measured during the liquid nanodispensing of attoliter droplets with an atomic force microscope tip. Due to the presence of a nanochannel drilled at the tip apex and connected to a reservoir droplet deposited on the cantilever, we observe a large variety of force curves during the deposition process. We propose a numerical method which accounts for most of the experimental observations. In particular, we clearly demonstrate the influence of the nanochannel diameter. This study leads to a better understanding of the mechanisms of liquid transfer from the tip to the surface and also provides a real time monitoring of the dispensing. Besides these applications, the method we use, which can handle a large variety of conditions and also complex geometries, may find a wide range of applications.