Objective: To evaluate the classification and factors associated with anxiety and/or depression in mothers of newborns in a neonatal intensive care unit and elaborate the nursing process after psychological testing. Method: A study conducted with 91 mothers of newborns in intensive care of northeastern maternity, through a Beck anxiety and depression characterization and inventory form. Results: Majority with severe anxiety (93.4%) and moderate depression (50.5%). There was statistical significance between anxiety with planned pregnancy (p=0.022) and vaginal delivery route (p=0.028), as well as depression with abortion (p=0.027) and mechanical ventilation (p=0.017). Conclusion: Route of delivery, unpaid occupation, income, kangaroo method adhering, supplementation, schooling, planned pregnancy, gestational age of birth and newborn weight impact emotional instability. Social support stands out as a protective factor for symptoms of anxiety and depression.
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