BackgroundNonalcoholic fatty liver disease (NAFLD) is among the most common chronic diseases of the modern world with a wide variety of factors including genetic, environmental and metabolic. The aim of this study was to verify the association between the degrees of hepatic steatosis at the abdominal ultrasound and the values of aminotransferases (aspartate aminotransferase (AST) and alanine transferase (ALT)), gamma glutamyl transpeptidase (GGT) and homeostasis model assessment-insulin resistance (HOMA-IR) index.MethodsA prospective, descriptive survey study, using a quantitative analytical examination, was conducted from July 2013 to July 2014. In the statistical analysis, values were expressed as median, first and third quartiles. We used the nonparametric Kruskal-Wallis test to compare the medians between the degrees of steatosis, adopted a statistical significance of 5% (P ≤ 0.05) and used the statistical program SPSS 22.0.ResultsWe diagnosed 233/800 (29.1%) patients with hepatic steatosis on routine ultrasound, and 65.7% were female. Regarding degrees, 119 had grade 1 (51.0%), 94 grade 2 (40.4%) and 20 grade 3 (8.6%). The median age of the patients with grade 1, 2 or 3 did not vary significantly (P > 0.05). The median body mass index (BMI), although clinically important because of its elevation, did not differ significantly (P > 0.05). ALT levels increased as the degree of hepatic steatosis has advanced as well as the levels of AST, GGT and HOMA-IR. AST values showed a greater association with the severity of fatty liver (P = 0.0001) than the ALT (P = 0.001).ConclusionsALT, AST, GGT and HOMA-IR are associated to the degrees of hepatic steatosis on ultrasound and can help in the selection of patients for the liver histological evaluation.

Patients with IGHD due to GHRH resistance exhibit objective reduction in the sleep quality, with changes in NREM and REM sleep, with no detectable subjective consequences. GHRH resistance seems to have a preponderant role over GHD in the sleep quality of these subjects.

The thyroid nodule is the presentation of various diseases of this gland. It is a very common clinical condition, particularly when employing sensitive methods of image. In this context, fine needle aspiration (FNA) is the main tool for differential diagnosis and the best value for money in the evaluation of nodular thyroid disease. This study aims to evaluate the profile of patients with thyroid nodules that are submitted to FNA. The sample consisted of 77 patients with thyroid nodule to be punctured. Data were collected for a period of 5 months in the Medical Center Sergipe Integrated (CEMISE), located in Aracaju / SE. The sample comprised 77 patients. Within the sample were 73 female patients (94.8%) and 4 men (5.2%), predominantly aged between 50 and 59 years. As the number of nodes, 57.1% of the patients (44 patients) had only one node to be punctured, while 42.9% (33 patients) had more than one. The majority (58.3%) of the nodules studied showed size = 1.0 cm. The familial history of thyroid disease was found in 42 patients (54.5%) and hypothyroidism personal history corresponded to 16.9% of the sample. The ultrasound examination showed 42 cases of thyroiditis. The results confirm the higher prevalence of thyroid nodules in the female population with advanced age. However, the finding of a greater number of nodes with small diameter puncture indication differs from existing literature.

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