Objective: Colorectal cancer (CRC) is a common and deadly disease. It is the third common malignancy in the world and the second leading cause of cancer-related deaths. Both environmental and genetic factors influence the risk of developing CRC. The clinical symptoms develop late in the course of the disease, and precursor lesions (adenomas) can be easily detected and removed. This study intends to evaluate the awareness of CRC in an Al-Qassim region and identify the (population) that can benefit from awareness and screening programs. Methods and Material: Quantitative observational, cross-sectional study using a self-administered electronic questionnaire survey was employed to include all males and females (Arabic speakers and older than 18) in the Al-Qassim region (March-June 2020). The questionnaire consisted of 13 multiple choice questions and two short answer questions in the Arabic language. The data were categorized according to gender, marital status, age, level of education, and residence to determine whether these demographic groups have a difference in Knowledge about CRC. Results: We used in the study an online distributed questionnaire, which was used before in another study. However, the assumed number needed for this study was 358; we collected 1430 responses (response rate is 400 %). In this study, the majority of the specimen was females 78 %, and 49.7 % had an age between 18 -32. the mean score of knowledge among the public in the Qassim region about CRC was 3.5573 ± 1.2664. the most symptoms related to CRC identified by the participants were blood in stool and abdominal pain, while the history of familiar CRC was the most known risk factors. The age, social status, and educational level had a significant correlation with the level of knowledge. Conclusions: Although older married individuals with higher education had more Knowledge of CRC than others, there were some misconceptions in the surveyed population regarding the function of the colon, how common the colon cancer and when they should be screened for colon cancer.

<b> Aim: </b> The study was conducted to analyse the recent peer-reviewed literature related to symptomatic spilled gallstones after Laparoscopic Cholecystectomy (LC). </br></br> <b>Materials and methods:</b> Articles published in the peer-reviewed journals of repute from 2012–2022 were evaluated for nine variables including: [I] age of the patient, [II] gender, [III] interval since index LC, [IV] index LC if emergent/difficult or elective/straightforward, [V] clinical presentation, [VI] spilled gallstones if detected by imaging, [VII] management, [VIII] approach to management, [IX] number of spilled gallstones. </br></br> <b>Results:</b> There were a total of 71 cases (37 males and 34 females) with a mean age of 63.7 years. The time of onset of symptoms from spilled gallstones, after index LC, ranged from 2 days to 15 years and 57 patients (80.3%) presented within 6 years. Forty (56.3%) patients were unaware of the fact that gallstone spillage had occurred during index LC. The retained gallstones were detected by imaging in 47 (66.1%) cases and they were multiple in 51 (71.8%). In 52 patients (73.2%), the stones manifested as abdominal abscess/foreign body granuloma; the other presentations being pelvic pain/fistula, intestinal obstruction, abdominal lump simulating malignancy, incidental finding of metastatic lesions and generalized peritonitis. The major approaches adopted to retrieve the retained stones included open surgery, laparoscopy and percutaneous drainage. There were two deaths (2.9%) due to spilled gallstones. </br></br> <b>Conclusion:</b> Retained gallstones represent a complication of laparoscopic cholecystectomy (LC) that has a potential to create morbidity and diagnostic difficulties, even after a substantial delay. There is a need to spread awareness about the adverse effects of spilled stones so that they are actively looked for and retrieved if gallbladder perforates during cholecystectomy. Whenever such a complication occurs, the patient should be properly informed and the details should be very clearly mentioned in the operation notes.

Paget’s disease of breast is a cutaneous malignancy of the breast involving the nipple-areolar complex that is often associated with underlying neoplastic lesions of breast parenchyma. This condition is often mistaken for a wide range of dermatological conditions, leading to delay in diagnosis. This review article revisits the etiology, clinical presentation, differential diagnosis, diagnostic work-up, natural history, management and prognosis of Paget’s disease of breast.

We aim to systematically review the psychological and social outcomes of patients post-bariatric surgery. The comprehensive search using keywords yielded 1224 records utilizing search engines PubMed and Scopus. After a careful analysis, 90 articles were found to be eligible for complete screening that collectively reported the use of 11 different BS procedures reported among 22 countries. This review is unique in that we collectively presented the result of various psychological and social outcome parameters (depression and anxiety, self-confidence, self-esteem, marital relationship, and personality traits) after BS. Regardless of the BS procedures performed, most studies over months to years presented a positive outcome of the parameters considered, while few presented contrasting unsatisfactory results. Thus, the surgery was not a cessation factor for these results to be permanent and thus suggested psychological interventions and long-term monitoring for assessing the psychological effects after BS. Additionally, the patient's endurance to check weight and eating habits after surgery is ultimately necessary.

Severe acute respiratory syndrome Corona virus 2 (SARS-CoV 2) was initially identified in December 2019 in Wuhan, China. The coronavirus disease (COVID-19) spread rapidly worldwide to become a global pandemic. Patients infected with this virus presented with fever, cough, shortness of breath, diarrhea, abdominal discomfort, and myalgia. Radiological examination of those patients revealed numerous findings like consolidation, ground glass opacity and can lead to lung collapse. Other uncommon features are presented such as pneumomediastinum, pneumothorax and lung cavity. Pneumothorax was one of the fatal complications mentioned in the literature as it increased the mortality of COVID-19 patients. We report four cases presented to the intensive care unit (ICU) with severe pneumonia complicated during the admission by pneumothorax, which mandated intervention by chest tube to stabilize the patient's condition. There were differences in age, sex, the treatment protocol used and the timing of the development of the pneumothorax. Pneumothorax should be kept in mind in patients admitted with pneumonia secondary to COVID-19, as it causes acute deterioration of the patient and needs urgent intervention.