<p class="abstract"><strong>Background:</strong> Whenever osteoporosis is discussed, the focus is on women; men are far less likely to receive a diagnosis of osteoporosis or osteoporotic fracture because of considerable gaps in knowledge on male osteoporosis. The aim and objectives were to study the prevalence of osteoporosis in males of above 40 year age group attending SMS Hospital Jaipur & to explore the influence of various modifiable and non-modifiable risk factors on BMD.</p><p class="abstract"><strong>Methods:</strong> Study Location: SMS Medical College and Hospital, Jaipur. Study design: Hospital based cross sectional study. Study period: April 2015 to December 2016. Sample Size: 200. Work up: After taking ethical clearance and informed verbal consent, demographic and clinical details were noted along with S- calcium, Vitamin D and bone mineral density assessment. Osteoporosis was defined as T score ≤−2.5 bone mass −1 to −2.5 and normal as >−1. Data thus collected was analysed with help of SPSS 22.0 through frequency, percentages, Mean, SD and ANOVA.<strong></strong></p><p class="abstract"><strong>Results:</strong> Prevalence of osteopenia and osteoporosis in the study population was 28.5% and 11.5%. Age wise maximum prevalence was in the age group 71-80 years (31.81%). Prevalence of osteoporosis was more among Muslim community 20.83%, more in low socio economic group (BPL). T score of study population was -0.3705±1.41. The mean BMI, S-Calcium, Vitamin D levels and T score values among osteopenic and osteoporotic patients were statistically highly significant when compared to patients without osteo-penic/porotic changes (p<0.05).</p><p><strong>Conclusions:</strong> Osteoporosis is a silent killer and prevention is better than cure as prevention requires simple steps such as good dietary habits, active life style, good control of systemic disorders, reduced intake of tobacco and alcohol.</p>
of numerous diseases, including some cancers. Skin autofluorescence (SAF) measurement in a non-invasive test that quantifies tissue AGEs. The aim of this study was to assess utility of SAF in prediction of malignancy in patients with gallbladder carcinoma (GBC). Methods: This prospective study comprised 29 patients (7 men and 22 women) with suspected or confirmed GBC who underwent surgery in the Department of General, Transplant and Liver Surgery of the Medical University of Warsaw between September 2018 and November 2019. SAF was based on 3 separate preoperative measurements on the anterior side of the forearm and expressed in arbitrary units (AU). Data on patients' weight, height, BMI, and diabetes were collected preoperatively. Results: Gallbladder carcinoma was diagnosed in 22 out of 29 patients (75.86%). Median SAF was 2.2 AU (IQR = 1.925 À 2.675) and 2.2 AU (IQR = 1.8 À 2.5) in GBC patients and individuals without cancer, respectively. There was no difference in SAF between patients with GBC and individuals without cancer (p=0.700). The lack of significant difference was unmodified by patient sex, presence of diabetes or BMI>25 (p=0.662, p=0.643, and p=0.629, respectively). Conclusions: Although SAF may have predictive value in some cancers, this study does not provide evidence for increased accumulation of AGEs in patients with GBC.
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