According to modern scientific literature, specific dermatoglyphic signs can be diagnostic markers of a person’s mental state. The purpose of the work is to identify the association of dermatoglyphic indicators with personality characteristics of practically healthy men of Ukraine. From the data bank of the materials of the research center of National Pirogov Memorial Medical University, Vinnytsya were taken the primary dermatoglyphic and questionnaires indicators of personality characteristics of 92 practically healthy men in the third generation residents of Vinnitsya, Khmelnytsky, part of Ternopil and Zhytomyr regions. Processing of dermatoglyphs was performed according to the method of Cummins H. and Midlo Ch. (1961) in the statement by Gladkova T.D. (1966). For objective evaluation of personality traits of practically healthy men, a number of leading indicators were determined, which included a number of properties of temperament (according to Eysenck), anxiety (according to Spielberger), accentuated personality traits (according to Shmishek), motivational orientation of personality (by Rotter), as well as the peculiarities of psycho-emotional organization of personality, aggressiveness, the level of distribution of asthenic and depressive personality manifestations (by the color test of Luscher), which were determined on the basis of personal use personality questionnaires and test methods. Factor analysis was performed in the “Statistica 6.1” license package. The main factors that indicate the association of personality traits of practically healthy men with some dermatoglyphic indicators are identified: “ridge count of fingers” (dispersion ratio – 13.22%) and “the magnitude of the angle atd” (dispersion ratio – 10.66%). Analysis of the obtained relationships of the interdependence of indicators of personality characteristics with dermatoglyphic indicators showed that with increasing indicators of ridge counts of the fingers and the delta index the degree of probability of growth of indicators of neuroticism according to Eysenck, situational and personal anxiety according to Spielberger, the accentuation of the character of the emotional and arousing types by Shmishek, subjective control in the field of health and illness according to Rotter, black and gray color by Luscher decreases, and the indicators of the accentuation of the character of the anxious and demonstrative types by Shmishek, the overall internality of the level of subjective control in the field of educational (professional) relations according to Rotter, blue and blue-green color by Luscher – is increasing. As the magnitude of the angle atd increases on both hands, the degree of likelihood of growth of neuroticism according to Eysenck, situational and personal anxiety according to Spielberger, accentuation of the character of the emotional, anxious and arousing types by Shmishek, blue color by Luscher increase, and indicators of accentuation of the character of the demonstrative type according to Shmishek, the general internality of the level of subjective control, in the field of educational (professional) relations and in the field of health and illness according to Rotter, blue-green, black and gray color according to Luscher – decrease. The use of factor analysis has allowed to determine the most significant correlation of indicators of personality characteristics with dermatoglyphic indicators.

The variability of fingerprints is widely used to identify a person in criminology, as adiagnostic-prognostic marker system in medicine and in the study of multi-vectoredethnogenetic processes in population surveys that cover different regions of the state.The purpose of the study is to outline the local structure of the male population ofUkraine by analyzing the indicators of digital dermatoglyphics for information on the vectorof evolution of the local population. Dermatoglyphic study was performed using H.Cummins and Ch. Midlo for 400 practically healthy men from different administrative-territorial regions of Ukraine. Statistical processing of the obtained results was carried outin the package STATISTICA 6.1 using nonparametric methods. High heterogeneity wasestablished on the basis of qualitative and quantitative indicators of signs of digitaldermatoglyphics among the following administrative-territorial groups: between theinhabitants of central and southern (22.22% of indicators), central and eastern (20.37% ofindicators) of central and western (15.74%), northern and southern (17.59% of indicators),northern and western (16.67% of indicators), northern and eastern (15.74% of indicators),western and eastern (12.04% of indicators) and southern and eastern (12.04% ofindicators) of the regions of Ukraine. Significant homogeneity was detected in terms ofqualitative and quantitative indicators of signs of digital dermatoglyphics inherent in men,residents of the northern and central regions of Ukraine (differences are recorded at 7(6.48%) indicators, as well as men living in the southern and western regions of thecountry (differences are recorded for 10-9.26% of indicators of only qualitativecharacteristics.) The obtained results allowed to distinguish two dermatological complexeson the territory of Ukraine: local north-central and local south-western. High taxonomicthe value for intra-population differentiation of the local level have: types of patternswith high intensity comb and the capacity of the pattern, especially the III and IV fingersof the right hand and I and II fingers of the left hand

Strengthening of global migration processes, often accompanied by an increase in crime and an increase in the number of unidentified individuals, necessitates the expansion of the use of indirect identification methods. In our opinion, involving dermatoglyphic analysis in cases of unidentified persons would help in forensic medical identification of the ethno-territorial membership of an unknown person. The purpose of the work is to identify a taxonomic complex of features of palmar dermatoglyphics at the local level that allow differentiating the regional affiliation of men in Ukraine. The study of dermatoglyphics of 400 virtually healthy men from 5 administrative-territorial regions of Ukraine was conducted using the method of H. Cummins and Ch. Midlo. Statistical processing of the results was carried out in the package “STATISTICA 6.1” using nonparametric methods. The set of signs of palmar dermatoglyphic was revealed, showing a high degree of heterogeneity between men from the following administrative-territorial regions of the country: central and eastern (20.0% of indicators), central and northern (16.9% of indicators), northern and western (16.9% of indicators), western and eastern (15.4% of the indicators) regions of Ukraine. Men from the northern and eastern (6.2% of the indicators), the south and west (6.2% of the indicator) and the southern and eastern (7.7% of the indicators) regions of Ukraine show a significant affinity for the features of palmar dermatoglyphics. In general, the high taxonomic value for intra-population differentiation of the local level have: the localization and saturation of the palm pattern, the size of the palm angles, the presence/absence of additional axial triads, the length of the segment c-t, the Cummins index.

The idea for this study is based on endothelial-dependent adaptation of hemodynamic circulation in pregnancy. The optimization of the circulatory component of the cardiovascular system (CVS) during pregnancy via blood pressure (BP), especially in physiological pregnancy (PhP), is accompanied by a clear overall increase in systolic characteristics of the pumping function of the heart. This orientation in cardiac output (CO) is unambiguously manifested throughout all three trimesters as with PhP—in a prone and standing position in total according to 24 characteristics out of 24 (P < 0.01), while for gestational endotheliopathy (PaP)—by 18 out of 24 (P < 0.05) clear restructuring of the dynamic organization of the circulatory state according to the anthropophysiological ratio to the hyperkinetic state according to CO in a standing position (type III) was noted with all blood pressure (BP) regimes. If the manifestation of type III under hypotonic, normotonic, and hypertonic regimes in BP was 8, 12, and 6%, respectively, then in the case of PhP, it was 21, 36, and 50%, respectively (P < 0.01), and for PaP, it was 48, 66, and 76% (P < 0.01). Hemodynamically identified heart failure (HF) syndrome, as the earliest preclinical circulatory endothelial-dependent form, is examined as a trigger of formation of perinatal pathology corresponding to preeclampsia.

Our work has revealed a rather low level of similarity in regard to the finger dermatoglyphics of somatically healthy men, 19-35 years old, between Ukraine’s north and west, north and south, center and west, center and south, as well as the palmar dermatoglyphics between central regions and the east, center and west, center and south. The obtained finger/palmar dermatoglyphics did not differentiate administrative-territorial local groups of men between the north and the center, south and west (quantitative characteristics); or palmar – between the north and west, north and east, south and west, south and east, north and center. The differences between the administrative and territorial division of dermatoglyphic signs are a reflection of the historical and cultural differences induced by migration, as well as the intensive process of mixing, in addition to the isolation of particular groups.

The formation of regional gene pools and the contribution of each of them to the formation of the population of Ukraine remains an actual topic of the present. The purpose of the study is to assess the contribution of each of the 5 territorial-administrative regions of Ukraine to the overall phenotypological picture of the finger dermatoglyphics of the male population of Ukraine. By the method of H. Cummins and Ch. Midlo conducted a dermatological study of 400 practically healthy men from 5 administrative-territorial regions of Ukraine. Statistical processing of the obtained results was carried out in the package “Statistica 6.1” using nonparametric methods. It was established that among practically healthy men of Ukraine without administrative-territorial distribution and representatives of various administrative-territorial regions 37.96% of reliable or tendencies of differences of information indicators of finger dermatoglyphics were revealed out of 108 analyzed parameters. The best information ability of quantitative (47.83%) indicators of finger dermatoglyphics was proved in comparison with qualitative (35.29%) indicators. The greatest number of differences in the signs of finger dermatoglyphics is established between men without division into administrative-territorial regions and men, residents of the southern (11.11%), eastern (10.19%) and western (8.33%) regions of Ukraine. Less number of differences from the overall picture of the country are found in men in the northern region, its rates significantly differed almost at the level of error and amounted to 5.56%. Indicators of finger dermatoglyphics of men in the central region in general do not differ significantly from those in general in Ukraine. Thus, the dominant component in the general phenotypological picture of finger dermatoglyphics of the male population of Ukraine has a central region whose rates were not significantly different from the country’s total, and to a lesser extent, the dermatoglyphics of the northern region. The obtained results indicate that the main genetic landscape of the gene pool of Ukraine, according to finger dermatoglyphics, forms the central and northern regions of the country.

Heterogeneity by types of genodermatoses inheritance from the group of ichthyosis, which include virtually all possible variants, is the basis for the application of one of the genetic methods of human study - the method of dermatoglyphics. The purpose of the study is to determine the peculiarities of the quantitative indexes of finger and palmar dermatoglyphics in men and women with ichthyosis. Dermatological examination was performed in 49 patients with ichthyosis and 136 dermatologically healthy persons. The sample of patients was conducted randomly. All persons received informed consent for conducting observations. Fingerprint and palm prints are obtained by scanning fingerprints on paper by the Futronic's FS8 USB2.0 Fingerprint Scanner using the ftrScanApiEx.exe program, and then transferring data to a personal computer. Processing of dermatoglyphics data was carried out according to the method of Cummins H. and Midlo Ch. (1961). The quantitative indices of both finger and palmar dermatoglifics were determined. The calculation of the received results was carried out in the licensed software package “Statistica 5.5”. The average sample values (M) and dispersion (σ) were determined in the groups of the subjects surveyed. Using the Mann-Whitney U-test determined the probability of differences in the results obtained for individual groups. A certain complex of quantitative signs of palmar dermatoglyphics is revealed, which is characteristic for men suffering from ichthyosis, which includes indexes of the intensity of the comb formations, the value of the length of the segment c-t, the value of the palm corners and the Cummins index. In women suffering from ichthyosis, such a complex includes, as in men, indicators of the intensity of the combs and the length of the segment c-t, except for which - also the value of palm comb accounts. Given the specific lamellar form of ichthyosis, the dermatoglyphic picture (monomorphism of established signs on both hands: the presence of a single 4-finger flexural fold, a pattern in the III interdigital gap, low localization of the carpal angle atd, and the presence of the ulnar loop, complicated by the internal pattern on the III finger of the left and the IV the finger of the right hand brushes), the authors concluded that the study of ichthyosis should be carried out necessarily for each form of ichthyosis separately, which significantly increases the resolution of the method of dermatoglyphics.

The aim: To investigate role of CD23, VEGF and PP13 in diagnostics of early and late preeclampsia, and their benefit for prediction of preeclampsia. Materials and methods: Investigation included 40 placentas from deliveries in women with preeclampsia (main group) and 40 placentas from physiological delivery in somatically healthy women, who had no complications during pregnancy (control group). Placentas in the main group were devided into two sub-groups (20 in each) – with early and late preeclampsia. Each group underwent both hystomorphometrical and immunohystochemical investigation with biomarkers CD23, VEGF and PP13. Results: Positive immunohystochemical reaction to PP13 was determined in all samples of syncitiotrophoblast of villi of chorion. Investigations showed that expression of PP13 in sub-groups with early and late preeclampsia was a lot lower comparing to control group (normal pregnancies). Positive immunohystochemical reaction to VEGF was determined in all samples of endothelia of the capillaries of the villi of chorion. Our investigation showed that expression of VEGF in sub-groups with early and late PE was a lot lower comparing to a control group. Immunohystochemical reaction to CD23 was comperatively lower in all samples in endothelia of the capillariesof the villi of chorion and cyncithiotrophoblast. Conclusions: Determined specialties of the expression of angiogenic factors ( PlGF, VEGF, endoglin) and production of PP13, by altered expression of VEGF, PlGF in first trimester of pregnancy, which is associated with lowest production of PP13, accompanied by placental dysfunction and preeclampsia.