locations; Dose to the prostate and pelvic node CTVs, rectum, bladder and femoral heads were calculated and presented for the total 20 plan scenarios of each patient. Results: For bony matching, prostate CTV dose degradation was prominent for interfraction prostate motion beyond prostate PTV margins. Potential prostate intrafraction motion would further degrade the prostate CTV coverage. Lymph node CTV dose coverages were not affected; for seed matching, dose degradation of pelvic lymph node CTV was prominent for interfraction prostate motion beyond pelvic node PTV margins. Dose coverage to prostate CTV were comparable to original treatment plans. For the seed matching image guidance, there were large dose variations to the rectum, bladder and femoral head among different prostate interfraction motion datasets. For the bony matching image guidance, there were large dose variations only to the rectum among different prostate interfraction motion datasets. Conclusion: Prostate interfraction motion from pelvic lymph node has significant impact on prostate and lymph node CTVs coverage. Due to this motion, different image guidance approach affect the target coverage and dose to OARs in a different manner.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.