Previously we initiated research into phosphorylation of the well-known flavonoid, dihydroquercetin I, with trivalent phosphorus reagents [1,2]. Now we report about the possibility of extending this reaction on quercetin II, a compound that has a more complex structure than flavonoid I.The partially protected quercetin derivatives, viz. quercetin 3,3`,4`,7-tetrabenzylate (III) and 3,3`,4`,7-tetraacetate (IV) contain a free hydroxy group in the C 5 position [3, 4]. Phosphorylation was carried out with 2-chloro-and 2-amido-4,4-dimethyl-1,3,2-dioxaphosphorinanes. The best yields of the target products were achieved when acid chlorides were used. 58 d go E d ; 6 d j R
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