Introduction: Type 2 diabetes mellitus is one of the major causes of increasing morbidity worldwide. Effective screening is carried out routinely for diabetic retinopathy, neuropathy, and nephropathy. Of late, studies have reported that cognitive decline can occur in people with diabetes, which could go undetected for a long period, and hence routine screening could be warranted. Methodology: Our objective was to study the prevalence of previously unknown mild cognitive impairment (MCI) in type 2 diabetic patients visiting a tertiary care center with the Montreal Cognitive Assessment (MoCA) test and to study the correlations of HbA1c, fasting blood sugar (FBS), postprandial blood sugar (PPBS), age, and duration of diabetes with the MoCA scores. Seventy patients with type 2 diabetes mellitus were included in the study. Patients with MoCA scores ≥26 were considered to have normal cognition (NC) and those with <26 MCI. Results: MCI was noted in 38 (54.29%) type 2 diabetes mellitus patients and NC in 32 (45.71%). Those with MCI had higher HbA1c (8.79 ± 1.85 vs. 7.78 ± 1.60), higher FBS (177.05 ± 62.48 vs. 149.38 ± 54.38), and PPBS (282.03 ± 85.61 vs. 214.50 ± 82.43), which were statistically significant. The cognitive domains of executive function, naming, attention, language, and memory showed a statistically significant difference between those with MCI and NC. There were no differences in the mean age, duration of diabetes, and educational status between the groups. Conclusion: The high prevalence of MCI in type 2 diabetic patients highlights the importance of implementing routine cognitive testing. The correlation of cognitive impairment with poor glucose control needs further studies to find out whether improving glycemic control will help improve cognition.
Background:Relaxation techniques like meditation have been found to be beneficial in reducing stress.Aim:The aim was to find out the effect of the Integrated Amrita Meditation (IAM) technique on the response to life changes.Materials and Methods:The IAM technique, progressive muscle relaxation (PMR) technique, and the Life Changes Questionnaire (LCQ) were used. LCQ was culturally adapted to the Indian population. One hundred and fifty subjects were randomized into IAM, PMR, and Control groups. LCQ scores were documented in all groups at 0 h, 48 h, 2 months, and 8 months after the training.Statistics Analysis:Within groups, comparison was done by the paired t-test and between groups by ANCOVA.Results:The new LCQ was analyzed using split-half reliability and was found to be having a correlation coefficient 0.96. On within group analysis, the IAM group showed a significant decrease in LCQ scores (P = 0.004) in the second visit which was maintained in the third (P = 0.003) and fourth visits (P = 0.001). Within the PMR group, there was a significant decrease (P = 0.006) in the third visit and fourth visits (P = 0.001). No significant change was seen within the control group in any of the visits. The decrease in LCQ scores in the IAM group was significant at the end of 8 months when compared to the Control group (P < 0.05) whereas the decrease in the PMR group was not significant in comparison with the control group.Conclusion:The IAM technique is an efficient tool in reducing stress as measured by LCQ.
The objective of the current study was to find out the effect of Integrated Amrita Meditation Technique (IAM) on blood pressure (BP), heart rate (HR), respiratory rate (RR) and IgA. One hundred and fifty subjects were randomized into three groups IAM, Progressive Muscle Relaxation (PMR) and Control. Baseline values were collected before giving the training for all the subjects and the IAM and PMR groups were given training in the respective techniques. BP, HR, RR and IgA were recorded manually at 0 h, 48 h, 2 months and 8 months after the first visit. HR was found to be reduced in the IAM group 48 h onwards and the fall sustained till 8 months (p < 0.05). IAM group showed significant drop when compared to the PMR group and control group in all the subsequent visits (p < 0.05). RR decreased significantly in the IAM group in the third and fourth visits (p < 0.05). RR of IAM showed significant decrease when compared to PMR and control from the third visit onwards. IgA showed significant increase in comparison with PMR and control in the third and fourth visits. BP did not show any difference in any of the visits. There was subject dropout from randomization to completion of the study, in all the three groups. The significant decrease in HR and RR and increase in IgA in the IAM group when compared to the PMR and control group shows the efficacy of the technique in reducing the physiological stress indicators for up to 8 months.
Caregivers are a largely understudied, unsung population who shoulder many of the social and psychological costs of mental illness. This study examines the load of caregiving during symptomatic and stabilised phases of the mentally ill and the various ways in which family members adapt themselves to give care. Drawing its data from 200 families with mental illness in Andhra Pradesh and Karnataka, the study diffuses the notion of care as physical, medical, psychological and social. The article focuses on how the gender of the affected person affects caregiving and underlines the indispensability of the family. Used to giving credit for any improvement to doctors and medicines, the study records the Indian Journal of Gender Studies 18(3) 405-424
Background: Recently, there have been a surge in research worldwide regarding relation of vitamin D with several diseases. Many neurological diseases like multiple sclerosis, Alzheimer's disease as well as other diseases like cardiovascular disease have shown positive correlation with vit. D de ciency measured according to the international level. Most of the research on possible role of vitamin D has been carried out in America and European nations, while there is paucity of research in low-and middle-income nations (LMICS) that are nearer to the equatorial area. In countries like Nepal, geographically they lie near to the equator and sunlight exposure is well enough and milk consumption is quite moderate. Thus, special consideration for vitamin D level in Asian population seems plausible. This will not only help us to cover the vitamin D de cient population but will help us to avoid excessive and unnecessary usage of it. Objectives: This study aims to detect the situation of vitamin D in Nepalese population and secondly to nd out the suitable normalized reference range for serum vitamin D in multi-ethnic Nepalese population. Methodology: This was a hospital based prospective study. A prospective study was conducted using purposive sampling technique with in-vivo and in vitro bio-physiological method to collect serum vitamin D level. After rigorous inclusive and exclusive criteria, a total of 107 subjects were collected. Result: The present study showed that 32% of participants had de cit serum Vitamin-D level (<15 ng/mL), 48% of subjects had insu cient serum level of Vitamin-D (15-<30ng/mL) and 20% of participants had su cient serum level of Vitamin-D (>30ng/mL). Study showed that there is lower degree of positive relationship of Body Mass Index (BMI) with Serum Vitamin-D level (r=0.162, p=0.094), History of chronic illness (χ2=0.10, p=0.03), timing of occurrence of stroke (χ2=11.41,p=0.017) and diagnosis (χ2=21.19, p=0.011) had signi cant association with Serum vitamin-D level at p<0.05. Conclusion: There is direct signi cant association of Serum Vitamin D with socio-demographic variables when international unit is considered. Neurological disorder showed positive association with serum vitamin D level.
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