Tuberculosis (TB) remains a major public health problem globally. Female genital tuberculosis (FGT) occurs mostly secondary to pulmonary tuberculosis, commonly by the haematogenous route. The main difficulties in the monitoring of treatment efficacy are connected with the use of the same technologies both in the diagnosis and cure estimation of FGT. Articles in tuberculosis journals rarely featured by equations. The aim of the present study was to elaborate new analytical approaches, in form of equation concerning FGT treatment efficacy identification. The general conclusion was created towards the RCSR (red cells sedimentation rate), PCR (polymerase chain reaction) and tuberculin skin-test, ultrasound and radial examinations: they are not reliable tools since both false-negative or false-positive cases were observed . Explanation of the mismatch of the most of identified alterations by means of ultrasound and radial examinations (CT and MRI) with the clinical status of women is explained by the prolonged maintenance of alterations caused by disease, up till several years after clinical recovery. Newly elaborated test based on 1 H-NMR (T 1 , T 2 ), relaxation times measurement in vitro being combined with the regression analysis models have a potential to assess the treatment efficacy of female genital tuberculosis in 70% of cases.
At present, immunotherapy is successfully used for the treatment of multiple malignant diseases, especially in the late stages of metastatic tumors, which until now, were difficult to treat using standards protocols. Positive therapeutic effects of immunotherapy were demonstrated in treatment of many common oncological diseases. However, despite the expressed positive effect, in some patients immunotherapy can demonstrate non-typical forms of the answer. To establish accurate diagnosis it is necessary to know radiological manifestations of immune-related adverse events (irAE), mainly, immune-mediated pneumonitis, colitis, hypophysitis, hepatitis and myositis. Early identification and the corresponding treatment of irAE may improve patient's outcomes.
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