Infrared thermography revealed characteristic abnormalities ia the emission patterns over the hands and feet of 16 young diabetics with or without manifest vascular complications. Infrared thermography seems to be a method well suited for fm'ther studies of circulation and metabolism in the hands and feet of diabetics.
Summary. Haematocrit, plasma volume and viscosity were not notably different at rest in fifteen diabetics from those in ten controls. After moderate exercise, plasma volume was reduced and haematoerit was increased significantly more than those in controls. In the diabetic subgroups based on varying degrees of dermal angiopathy, no significant differences were demonstrated. In circulatory steady state during exercise the diabetics responded with a marked increase of systolic blood pressure. The amount of filtrate from the vascular bed to the interstitial tissues was not correlated to increasing systolic pressure. The difference in work intensity between the groups is not of such an order that it can be assumed to influence haematoerit or plasma volume. These findings may indicate increasing" permeability of the capillary walls because of changes characteristic of diabetic microangiopathy.
Effet de l'exercice sur l'hdmatocrite, ~e volume plasmatique et la viscositd clans le dgab~te sucrdRdsumd. L'h6matocrite, le volume plasmatique et la viseosit6 ehez 15 diab4tiques n'4taient pas notablement diff4rents au repos par rapport aux dix t4moins. Apr@s un exereiee mod4r6, le volume plasmatique diminuait et l'h@matoerite augmentait significativement plus que ehez les t4moins. Darts les sous-groupes diab4tiques, bas4s sur les degrgs variables d'angiopathie dermique, on n'a pas d4montr4 de diff6renees signifieatives. Darts des conditions eireulatoires stables, pendant l'exereiee, les diab4tiques r4pondaient par une augmentation marqu4e de la pression systolique du sang. La quantit@ de filtrat du lit vaseulaire aux tissus interstitiels n'4tait pas en eorr41ation avee la pression systolique accrue. La diff@renee darts l'intensit4 du travail entre les groupes n'est pas telle qu'elle puisse influeneer l'h6matoerite ou le volume plasmatique. Ces d6eouvertes peuvent indiquer une perm6abilit6 accrue des parois eapillaires k cause des modifications earaet6ristiques de la microangiopathie diab6tique.
A controlled study of the peripheral circulation in 47 diabetics has been performed with the aid of thermography. Infrared emission patterns over hands and feet revealed asymmetries and/or deviations of the normal skin temperature distribution in all diabetics. The thermographic findings of the diabetic patients were in most cases distinctive, with an asymmetric decrease in the emission levels over one or more toes or fingers. These thermographic abnormalities are interpreted as reflecting probable vascular disturbances, which are characteristic of diabetes mellitus.
The gastric secretory response to insulin administration has been investigated in eleven diabetic patients in order to study their vagal function. The mean duration of the disease was 16 years. One patient suffered from diarrhoea. The other diabetic patients were free of symptoms from the gastrointestinal tract. From the criteria in the literature for surgical vagotomy, some patients with long duration of the disease and with severe signs of vascular and neurological involvement exhibited impaired vagal function. This supports the theory that impaired vagal function is the cause of disturbances of the gastrointestinal tract in diabetes mellitus.
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