Clinical and histological features in 40 patients of a pigmentary disorder, hitherto undescribed in Indians, are presented. The resemblance of this entity to somewhat similar disorders seen in other parts of the world and its possible relation to lichen planus is discussed.
Light and electron-microscopic studies were performed on the amelanotic and adjacent normal-appearing skin in patients with vitiligo. The amelanotic skin revealed complete loss of pigment and absence of melanocytes. In addition to severe degenerative changes of melanocytes, varying degree of damage was also seen in the keratinocytes of normal-appearing skin adjacent to amelanotic skin.
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