Occasional accounts of gonococcal infection of the throat have appeared in the literature since the 19th century, but no systematic investigations were published before the 1970s. Reports have now been made on the incidence, diagnostic criteria, paths of infection, symptomatology, complications, and treatment of the condition (Bro-J0rgensen and Jensen, 1973). We have studied certain aspects of gonorrhoea of the throat in two Swedish populations. Material and methodsThe series comprises 3,271 consecutive cases of gonorrhoea seen at the venereological clinics in two Swedish towns, Norrkoping (2,179 cases) and Linkoping (1,092 cases), during the years 1971 to 1974.In all cases swabs were taken from throat and urethra, and in women from the cervix and rectum also. Throat specimens were confined to the tonsils, and the same swab was used on both sides. In 24 patients with confirmed tonsillar gonorrhoea, samples of saliva were taken from the anterior part of the mouth before treatment. All specimens were taken with a cotton-wool swab and placed in Stuart's medium for transport to the laboratory.Culture was carried out on blood agar plates with and without antibiotics ; in the case of tonsillar and rectal swabs antibiotics were always present in the media (Vancomycin® + colistin + nalidixic acid). The colonies were examined by Gram staining, oxidase testing, and fermentation with glucose, laevulose, and maltose. The resistance to penicillin, ampicillin, and other agents was determined, a minimum inhibitory concentration (MIC) of 0-06 ,ug./ml. being set as the upper limit of full sensitivity for ampicillin.The standard treatment for ano-genital gonorrhoea was a single dose of 2 g. ampicillin + 1 g. probenecid by mouth. When gonococci were demonstrated in the throat, treatment was carried out in accordance with one of the schemes shown in Table I.After treatment the patient was re-examined and cultures were taken at least twice, at intervals of at least 1 week. In cases of tonsillar gonorrhoea, four cultures were taken after treatment, at intervals of 4 to 7 days.
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