In our study, growth discrepancy between twins was significantly correlated to adverse neonatal outcomes, while intertwin delivery time was not an influencing factor. So, in line with this result, in our clinical practice, we do not use a fixed time in which both twins should be delivered, neither in monochorionic nor in dichorionic pregnancies, when fetal wellbeing was demonstrated during labor.
It seems that some thrombophilias and a combination of thrombophilic factors carry a greater risk than others for a given adverse outcome. Further studies are needed to check the link between thrombophilic gene mutations and adverse pregnancy outcomes, such as recurrent miscarriages and deep venous thrombosis.
infertile couples the maximal chance of conception. As perifollicular vascularization is related to a better oocyte competence leading to the development of higher quality embryos, we used 3D power Doppler (pD) to relate perifollicular blood flow indexes to oocyte maturity, showing that increasing in perifollicular blood flow reflects into a better oocyte quality and embryo viability. 3D pD measurements of perifollicular blood flow changes reflect oocyte maturity and can be used as a useful tool to establish which oocytes to inject/fertilize to improve IVF outcome. Results: Among the 194 patients 31% had endocrine abnormalities, 19% had inherited trombophylia, 17% had antiphospholipid antibodies (aPL) syndrome, 7% had a müllerian uterine abnormality, 2% had genetic abnormalities, 4% had an autoimmune disease and in 20% of patients none of the investigated factors were found. The higher mean PI values were observed among patients with aPL syndrome (2.7 ± 0.9) and uterine abnormalities (2.7 ± 0.76). These values were significantly higher with respect to that found in the other groups of patients (2.0 ± 0.57 in endocrine abnormalities group, 2.1 ± 0.7 in inherited thrombophilia group, 2.3 ± 0.95 in patients with autoimmune pathology and 2.1 ± 0.28 in genetic anomalies group). Finally the highest mean PI values (2.8 ± 0.42) were found in patients with otherwise unexplained RSA. Conclusions: These data suggest that the increased resistances to uterine blood flow may be an important contributing factor to some causes of RSA and the cause of some previously unexplained RSA. In these patients the assessment of uterine perfusion could allow new therapeutic approaches.
P12
P13: NEW TECHNOLOGIES AND GYNECOLOGICAL ONCOLOGY P13.01 3D/4D examinations in cervical cancerA. Kratochwil
Univ. Clinic Radiationtherapy and Biology, AustriaObjective: It is the intention to examine the possibilities of 3D/4D ultrasonic examinations in cervical cancers. In cancers 4 main questions are of importance; tumour staging, formation of metastases, treatment planning, post therapeutic follow up. Method: A 730 Expert GE system was used. Because of the variety of demands different transducers were in use : Vaginal probe 5-9 MHz, rectal probe 6-10 MHz, abdominal probe 2-5 MHz, and a small part transducer 5-12 MHz. Diagnosis was further improved by Volume Contrast Imaging, PM Doppler, B Flow, and VOCAL for exact assessment of the tumour volume.Results: Only by 3D examination the tumour is accessible and measurable in its full extend. Tumour delineation is improved by Volume contrast imaging. Power Mode and B Flow are able to demonstrate tumour vessels. Parametrical infiltration is detectable by rectal examination only. The local status is supplemented by the examination of the liver; VCI improves the detection of small metastases. Hydronephrosis as consequence to urethral obstruction is easily detectable. Para aortic lymph nodes, and nodes at the lateral pelvic wall larger than 1 cm, are demonstrable with nearly the same accuracy as by MR and CT exa...
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