Methods: A stroke patient with hot flashes was treated for 4 weeks with acupuncture, herbal acupuncture, and herbal medicine. We then evaluated the frequency, intensity, and score (frequency×intensity) of the hot flashes, as well as the Pittsburgh Sleep Quality Index (PSQI), which shows subjective sleep quality.Results: After 4 weeks of traditional Korean medicine (TKM) treatment, the patient showed reductions in the frequency of hot flashes from a score of 7 to 4, the intensity of hot flashes from a score of 4 to 2, the scoring (frequency×intensity) of hot flashes from 28 to 4, and the PSQI from 13 to 4.
Conclusions:This study validated the effect of TKM as a treatment for hot flashes in patients with stroke.
The aim of this study was to perform a systematic review and meta-analysis of randomized controlled trials (RCTs) that applied herbal medicine to treat viral hepatitis B and C in order to determine the therapeutic efficacy of herbal medicine.EMBASE, Pubmed, NDSL, KMBASE, KISS, KISTI, Koreamed, Koreantk, and Oasis databases were searched to identify RCTs. The selected studies were assessed by the Cochrane group's risk of bias tool.A total of 15 RCTs were selected, and the hepatitis B virus (HBV) DNA reduction was significantly higher in patients treated with herbal medicine combined with Western medicine than in patients treated with herbal medicine. Herbal medicine combined with Western medicine was also superior to Western medicine alone in achieving hepatitis B e-antigen (HBeAg) and alanine aminotransferase [ALT] reduction. Only herbal medicine alone was not superior to Western medicine treatments in achieving HBV DNA, HBeAg, and ALT reduction.
Objectives: The aim of this study was to investigate the trends in research on non-alcoholic fatty liver disease (NAFLD) using Korean traditional medicine.Methods: This review included studies related to the treatment of NAFLD, irrespective of the year of publication. The search terms were “nonalcoholic fatty liver disease”, “non-alcoholic fatty liver”, “nonalcoholic hepatitis”, “herb”, “herbal medicine”, “acupuncture”, and “traditional medicine”. The studies were analyzed according to the type of research.Results: After screening, 179 studies were selected from the 592 identified by the search. The types of studies were 151 in vivo or in vitro studies, 5 randomized controlled trials, 12 case reports, 2 unspecified clinical studies, 8 review articles, and 1 article that was difficult to classify.Conclusion: Analysis of the trends in Korean traditional medicine treatment by reviewing the studies on NAFLD revealed a focus on experimental studies rather than clinical studies. Therefore, multifaceted and well-designed studies are needed.
AC a s eR e p o r to fC o u g hi naP a t i e n twi t hMe t a s t a s i st o L u n gI mp r o v e db yK o r e a nMe d i c i n e Na-k y u n gCh o ,Mi-j u n gYo o n ,Ho n g-s i kCh o i ,S e u n g-moKi m,Ky u n g-s o o nKi m D e p t .o fK o r e a nI n t e r n a lMe d i c i n eo fH e p a t o l o g y ,C o l l e g eo fK o r e a nMe d i c i n e ,D a e g uH a a n yU n i v e r s i t y
Purpose : The object of this study was to observe anti-cachexic effects of Kwibi-tang extracts (KBTe) on non-small cell lung carcinoma (squamous epithelial carcinoma), NCI-H520, xenograft Balb/c nu-nu nude mice.Methods : Three different dosages of KBTe, 50, 100 and 200 ㎎/㎏ were orally administered once a day for 42 days from 11 days after tumor cell inoculation. Six groups, each of 8 mice per group were used in the present study. Changes on the body weight, the epididymal fat weight and serum IL-6 levels were detected with the thicknesses of deposited cervical brown adipose tissue and their mean diameters to monitor the tumor-related anticachexic effects.Results : Deceases on the body weight and gains were also demonstrated in tumor-bearing control with increases of serum IL-6 levels, decreases of epididymal fat pad weight, atrophic changes of cervical brown adipose tissues. These are means that tumor-related cachexia are induced by tumor cell inoculations in the present study. However, these tumor-related cachexia were markedly inhibited by all three different dosages of KBTe treatment as compared with tumor-bearing control. 5-FU showed somewhat deteriorated the tumor-related cachexia in the present study.
Conclusion :The results obtained in this study suggest that over 50 ㎎/㎏ of KBTe showed favorable anticachexic effects on the NCI-H520 cell xenograft. However, detail mechanism studies should be conducted in future with the screening of the biological active compounds in this herb.
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