Herbal Medicine for the Treatment of Viral Hepatitis B and C: A Systematic Review of Randomized Controlled Trials

Abstract

The aim of this study was to perform a systematic review and meta-analysis of randomized controlled trials (RCTs) that applied herbal medicine to treat viral hepatitis B and C in order to determine the therapeutic efficacy of herbal medicine.EMBASE, Pubmed, NDSL, KMBASE, KISS, KISTI, Koreamed, Koreantk, and Oasis databases were searched to identify RCTs. The selected studies were assessed by the Cochrane group's risk of bias tool.A total of 15 RCTs were selected, and the hepatitis B virus (HBV) DNA reduction was significantly higher in patients treated with herbal medicine combined with Western medicine than in patients treated with herbal medicine. Herbal medicine combined with Western medicine was also superior to Western medicine alone in achieving hepatitis B e-antigen (HBeAg) and alanine aminotransferase [ALT] reduction. Only herbal medicine alone was not superior to Western medicine treatments in achieving HBV DNA, HBeAg, and ALT reduction.

Exploration of the Potential and Mechanisms of Diabetic Cognitive Disorder Modulation by Daehwangmokdanpi-tang through a Network Pharmacological Approach

“…당뇨병은 인슐린의 분비 부족 또는 기능 이상으로 나타나는 대사 질환의 일종으로 혈중 포도당의 농도 가 높아지는 고혈당증을 특징으로 한다 1) . 당뇨병은 신장 질환, 시력 상실, 심혈관 질환 및 말초성 신경 병증 등을 유발할 수 있지만, 인지장애가 당뇨병의 합병증으로 일어날 수 있다는 사실은 비교적 덜 알 려져 있다 2,3) . 당뇨병 환자는 실행 지연, 정보 처리 속도 저하 등의 장애에서부터 치매와 같은 심각한 인지 손상까지의 다양한 인지장애를 겪을 수 있지만, 당뇨병 환자에서 어떠한 메커니즘으로 인지장애가 일 어나는지는 아직까지 명확하게 밝혀지지 않았다 [4][5][6] .…”