To the Editor: Vaccination has played a major role in eradicating communicable diseases. 1 Because health care workers (HCWs) serve in the forefront during pandemics, they are particularly vulnerable. Thus, in the coronavirus disease 2019 (COVID-19) pandemic, it was imperative to vaccinate frontline workers as quickly as possible and ascertain the extent of protection offered by vaccination.

Patients admitted with dimethyl organophosphate poisoning have a worse outcome compared with diethyl organophosphate poisoning for clinically relevant patient outcomes.

Subclinical chorioamnionitis has been impliw x cated as a cause for stillbirths 1᎐3 . However, it is unclear if chorioamnionitis is an independent risk factor for unexplained stillbirth. We used a prospective case᎐control design to determine the role of subclinical chorioamnionitis in unexplained stillbirths in India.Women with unexplained stillbirths at or beyond 26 weeks gestation were the cases. Two controls were selected for each case, matched for gestation and sex of infant. The first group comprised women who had stillbirths with identifiable causes; the second included women who had delivered live babies. For each case, the next eligible women were selected as controls. Assuming a

Hypoalbuminemia and delirium predicted poor outcomes in our patients. We found a high prevalence of ESBL infections in this study. Further research is required to assess the efficacy of aggressive management of delirium and low albumin in improving health and cost outcomes.

Introduction-Elderly patients have multiple comorbidities requiring treatment. Drug prescription plays an important role in the care of the elderly. Inappropriate prescribing is considered a major public health issue, given its direct association with substantial morbidity, mortality and health service costs that result from adverse drug reaction. The aim of the present study was to estimate the prevalence of inappropriate medication use in hospitalised elderly, as defined by Beers Criteria 2012. The risk factors associated with the use of potentially inappropriate medications were also evaluated. Materials and Methods-This study was done from April 2013 to August 2014 in the department of Geriatrics of a tertiary care centre in South India. Demographic parameters, comorbidities, pharmacokinetic parameters, cognitive and functional status and details of drugs (over 2 weeks) were collated. Results-Total of 280 hospitalised patients were included. The prevalence of potentially inappropriate medication use in our study was 33.2% as per Beers criteria version 2012. Use of drug with anticholinergic activity was found in 13.4% and among sedatives major contributior were benzodiazepines in 6.5% subjects. Age, depression and polypharmacy were found to be independent risk factors for potentially inappropriate medication use. Conclusion-Present study showed high prevalence of inappropriate drug use in the elderly. Effective intervention to optimise drug prescribing in elderly is therefore needed to prevent adverse drug reactions, drug interactions, cognitive impairment, falls and mortality.