Serial serum assays of immunoreactive FSH before, during and after a 4 h intravenous infusion of human follicle stimulating hormone (hFSH) in five healthy men revealed two disappearance rate constants with corresponding mean half-lives of 2.9 and 50.6 h. The mean distribution spaces calculated for the fast and slow component were 4.36 I and 75.9 1 respectively. The average value for the metabolic clearance rate was 17.2 ml/min and for the 225 Acta endocr. 81, 2 là I. Kinetics of human follicle stimulating hormone
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