No abstract

EGFRIs may cause cutaneous adverse effects through selectively perturbing innate immune responses induced by commensal and pathogenic bacteria.

References1 Al Samarai AG. Prevalence of skin diseases in Iraq: a community-based study. Int J Dermatol 2009; 48: 734-739. 2 Khalifa KA, Al-Hadithi TS, Al-Lami FH, et al. Prevalence of skin disorders among primary-school children in Baghdad governorate, Iraq. East Mediterr Health J 2010; 16: 209-213. 3 Basra MK, Finlay AY. The family impact of skin diseases: the greater patient concept. BMJ 2007; 156: 929-937. 4 Hay RJ, Estrada Castanon R, Alarcon Hernandez H, et al.

Introduction: Polyacrylamide hydrogel has been considered a safe and biocompatible soft tissue filler, and it has been widely used in cosmetic procedures. However, recent studies have revealed some complications with polyacrylamide filler injections. Case Report: We present the case of foreign-body granulomas of the glabella, which subsequently formed an infectious ulcer 3 years after a polyacrylamide injection. An immunohistochemical evaluation of the foreign-body granulomas was performed in order to study the relationship between foreign-body granulomas and immune response. Conclusion: We believe that our analysis of foreign-body granulomas 1 and 3 years after a filler injection may contribute to revealing the mechanism of chronic and intractable infections after filler injections.