Bacterial meningitis is still life-treating disease, which cause about 1.2 million cases and it is responsible for over 100 thousand of deaths across the globe. [2][ The most common pathogens which case the disease are Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae and Listeria monocytogenes. Morbidity is significantly higher in Africa, than in other regions in the world. Region of the highest frequency of new cases is located in sub-Saharan Africa and called meningitis belt. Vaccination campaigns against bacterial, mostly meningococcal were conducted in some of these regions and the benefits of it were seen [5]. Young children and elderly patients are predisposed to have bacterial meningitis. In pediatric population the disease usually presents as fever, seizures, vomiting, chills, altered mental status and stiff neck. [4] Development of each country have impact on mortality and morbidity among children. [6] Elderly patients, because of their comorbidity are also predisposed to bacterial meningitis. Diseases like diabetes mellitus, alcoholism, cancer, HIV/AIDS or being after splenectomy may make the patients susceptible for bacterial invasion of CNS. Also, every factor which interrupt blood-brain barrier, like trauma or surgery may cause the infection. Intracerebral hemorrhage can be consequence of the infection, which cause other complications like impaired consciousness, focal neurological deficit, need of mechanical ventilation and seizures. It was noticed that in most of cases bacterial meningitis had S.pneumoniae etiology.

Energy drinks are very popular nowadays. The number of people consuming this type of drink is growing every year, not only in the adult group but also in the population of adolescents and children. For many people, they are an alternative to stimulating coffee. In addition to the desired effects such as reducing fatigue, improving concentration and increasing physical and mental performance, energy drinks can also have adverse effects. The substances they contain, such as caffeine, taurine and large amounts of carbohydrates, may contribute to an increased risk of cardiovascular complications, metabolic and gastroenterological diseases, and mental disorders. [1] The aim of the article is to present the negative effects of consuming energy drinks in the population of adolescents and children.

COVID-19 is one of the biggest challenges to medicine ever. Because of its dissemination in population effective drug to cure it was needed. There were some trials on antiviral drugs like lopiravir/ritonavir, remdesivir, darunavir/cobicistat, favipiravir, molnupiravir, discovered originally in order to treat other diseases. Only remdesivir and molnupiravir seem to be beneficial for patients with COVID-19, both of them are approved in therapy in a large number of countries allover the world. [2] Another very important group of drugs used in trials against COVID-19 was immunomodulatory drugs. Some of them, like chloroquine/hydrochloroquine was very promising, but finally there were no evidences of its benefits found. [2] Corticosteroids used in moderate and severe COVID-19 caused general improvement of clinical status and decreased mortality. Interesting and quite promising may be use of interferons but for now lack of evidences does not allow to make clear statement about its benefits. There are some argumentations for natural methods of COVID-19 treatment. Dietary recommendations, vitamin and microelements supplementation may be helpful in the therapy and in addition may not have any adverse effects. Also, herbal mixtures, developed centuries ago in China found usage during COVID-19 pandemic. After analysis of thousands of cases Traditional Chinese Medicine can be considered as one of the most successful attempt in combating COVID-19. [6]

Coffee is one of the most consumed beverages among adults. Popular for its stimulant properties, it is also appreciated for its taste and is an essential part of many people's daily lives. Coffee, in addition to caffeine, contains macroelements such as sodium, potassium and magnesium, which ensure the proper functioning of the body, as well as polyphenols which are characterised by their anti-inflammatory properties. [1,2] Atrial fibrillation is the most common arrhythmia and caffeine is often considered a potential risk factor. [3] The purpose of this article is to evaluate current scientific reports on the relationship between coffee consumption and atrial fibrillation.

Arterial hypertension is a serious clinical problem in everyday medical practice. It mainly affects adult patients, but is also increasingly common in children and adolescents. Making a diagnosis is possible thanks to systematic measurements of blood pressure during routine medical visits, while maintaining appropriate rules and referring to adequate biological norms - centile charts. Arterial hypertension in children and adolescents may be primary, but much more often than in the adult population, it occurs secondary to diseases of other organs and systems. Early diagnosis of hypertension in the developmental age gives a chance to implement adequate therapy by treating the underlying disease, lifestyle modification or pharmacological treatment. The aim of effective therapy of hypertension is to prevent the occurrence of early and long-term complications of the disease, as well as to reduce the risk of hypertensive emergencies.