Background: OSMF is an oral precancerous condition with a high potential for malignant transformation. The main etiologic factor linked to OSMF is gutkha and tobacco chewing. Management of OSMF includes various therapies and drugs where the use of antioxidants has proven to be efficacious. Aim: The present study was conducted to compare and assess the efficacy of Lycopene antioxidant alone to its combination with intralesional injection of Hyaluronidase for managing the subjects with OSMF.Material and Method: The study included 54 subjects having stage 2 OSMF and were divided into 2 groups where the group I subjects were given lycopene daily in a dose of 8mg in two equal doses, whereas, group II subjects were given lycopene daily in a dose of 8mg combined with intralesional hyaluronidase injection of 1500 IU twice in a week for 3 months. VAS and inter-incisal mouth opening were assessed at baseline and 90th day after treatment completion.Results: At baseline, interincisal opening in Group I was 25.18±3.03mm and was 24.56±3.92mm in Group II. This difference was statistically non-significant with p=0.5184. On the 90th day, the last day of the study, interincisal opening in Group I was 29.34±3.19mm, whereas, in Group II was 32.39±3.24mm.

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Background: The association between cardiovascular diseases and periodontitis had different pathophysiological mechanisms involved. These mechanisms are both inflammatory and microbial. Furthermore, the possible association between two diseases can be explained by common risk factors. Aims: The present trial was carried out to establish a relation between coronary artery disease and periodontitis. Materials and Methods: One hundred and twenty-six participants advised for the angiography were included. Periodontists determined the presence of periodontitis in all participants followed by lipid profile, C-reactive protein (CRP) levels, and blood coronary angiography was then performed. The collected data were subjected to the statistical analysis, and the results were formulated. Results: The level of CRP in participants with and without coronary artery disease was 0.66 ± 1.52 and 0.53 ± 1.01, respectively, which was nonsignificant with a P = 0.63. Nonstatistically significant difference was seen in values of cholesterol and blood glucose in participants with and without coronary artery disease ( P = 0.28 and P = 0.53). The mean tooth loss in participants with coronary artery disease was 14.2 ± 6.4 and in participants with no coronary artery disease was 11.8 ± 6.5, and such difference was statistically significant ( P = 0.05). Conclusion: The present study establishes an association between poor oral health, periodontitis, and coronary artery disease. This study demonstrates that tooth loss which is an important feature of periodontitis is significantly associated with coronary artery disease.

Background: Dental fear and anxiety (DFA) is considered the main reason of dental negligence which can lead to detrimental oral health as well as overall health including psychological well-being and quality of life in an individual. Aims: The present trial was aimed to assess the skill and knowledge of dentists in managing DFA in adult subjects, to evaluate the available strategies used in treating such subjects, and to find the need for further education. Materials and Methods: The present study was an original survey and questionnaire trial, which was distributed to the 82 dentists. The collected data were subjected to statistical evaluation and the results were formulated. Results: Educating and motivating subjects was found to be effective by 62.19% (n = 51) of dentists followed by successive approximation, and muscle relaxation was considered highly ineffective by one responder (1.21%). Music and reduced waiting time in the clinic appeared to be the most effective strategy as responded by 56.09% (n = 46) of dentists. Attempting treatment in various visits than a single seems to be a highly ineffective technique by 4 dentists (4.87%). Conclusion: Within its limitation, the study showed that the application of various behavior modification techniques can be effective in alleviating DFA in adult patients.