Whole-body MRI with DWI can be used for bone metastasis assessment of NSCLC patients as accurate as bone scintigraphy and/or PET/CT.

http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.10100245/-/DC1.

MRI with ultrashort TEs is potentially as useful as quantitatively assessed MDCT for pulmonary function loss assessment and clinical stage classification of COPD in smokers.

DWI may have better potential than FDG PET/CT for prediction of tumor response to therapy in NSCLC patients before chemoradiotherapy.

STIR is more sensitive for detection and subtype classification than DWI.

The likelihood of lymph node metastasis increases with an increase of the SUV of a primary lung cancer.

No abstract

Purpose: To compare the utility of phase contrast MR imaging (PC-MRI) for assessment of pulmonary flow and pressure estimation with that of right heart catheterization and echocardiography (cardiac US) in patients with pulmonary arterial hypertension (PAH). Materials and Methods:Twenty consecutive patients with suspected PAH underwent PC-MRI, cardiac US, and right heart catheterization. In each patient, PC-MRI was acquired by cine 2D-PC method on a 1.5 Tesla scanner, and stroke volume (SV) and pulmonary arterial systolic pressure (PASP) were assessed by using the modified Bernoulli's equation. To evaluate the agreements of SV and PASP among the three methods, correlations and limits of agreement among the three methods were statistically assessed by using the Bland-Altman's analyses. Results:The correlations and limits of agreement for SV and PASP between PC-MRI and catheterization (r ¼ 0.96, r 2 ¼ 0.94, 1.1 AE 6.9 mL and r ¼ 0.94, r 2 ¼ 0.88, À3.2 AE 14.5 mmHg, respectively) were better than between cardiac US and catheterization (r ¼ 0.01, r 2 < 0.01, 8.9 AE 42.1 mL and r ¼ 0.86, r 2 ¼ 0.72, À5.9 AE 27.7 mmHg, respectively).Conclusion: PC-MRI is more compatible with right heart catheterization than cardiac US in pulmonary flow and pressure estimation. EVALUATIONS OF PULMONARY flow and pressure are essential for proper and prompt therapy for pulmonary arterial hypertension (PAH), and many different modalities have been developed to quantify the pulmonary circulation (1,2).To assess disease severity and therapeutic effect in PAH patients, objective method for assessment of pulmonary flow and pressure has been right heart catheterization based on indicator dilution theory, which is considered the most accurate method in routine clinical practice (3). Despite accuracy of this technique, this method is invasive and cannot be adapted to all PAH patients. Therefore, other alternative noninvasive measurements are warranted. Currently, Doppler echocardiography (cardiac US) is the most widely adopted method for noninvasive measurement of pulmonary arterial pressure, and its clinical applications have already been confirmed (4,5); however, cardiac US basically has a disadvantage in quantitative measurement due to limited acoustic window especially for evaluation of pulmonary circulation and the observer dependency for data acquisition.Recently, two-dimensional (2D) or three-dimensional (3D) phase-contrast (PC) MR imaging is considered as another noninvasive method for assessment of hemodynamics of pulmonary or cardiac circulation (6-8). These techniques provide us the opportunity for accurate estimation of pulmonary circulation