We treated a 65-year old woman with diffuse uveitis and an intraocular mass. The diffuse uveitis resolved with the administration of corticosteroids, but the intraocular mass did not respond to treatment. A transscleral biopsy of the lesion was performed. Histophathological study revealed non-Hodgkin’s large-cell lymphoma. Immunohistochemical analysis showed that the tumor cells were derived from B-cells. The intraocular mass diminished after radiation therapy. The transscleral biopsy proved useful in establishing the correct diagnosis.
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