Coronavirus infections are associated with a wide range of bacterial and fungal co-infections. Use of steroids, monoclonal antibodies and broad spectrum antibiotics along with underlying pathogenesis may alter body homeostasis and exacerbate preexisting fungal disease. We report the cases with COVID-19 infection, which, after the course of the treatment, presented with various forms of mucormycosis infection.
Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. Besides affecting respiratory tract it also causes systemic inflammation which also leads to coagulopathy affecting major blood vessels in the body. This report describes a case of aortic, renal artery thrombosis in a patient admitted for evaluation of abdominal pain and detected to have high titer of SARS COV-2 IgG antibodies with no prior history suggestive of typical COVID-19 infection (COVID-19 RTPCR and antigen tested negative).
Introduction: Cryptogenic Organizing Pneumonia (COP) earlier known as 'Bronchiolitis Obliterans with Organizing Pneumonia' (BOOP), is a rare lung condition in which the bronchioles, alveoli and the walls of small bronchi become inflamed and plugged with connective tissue. The condition is called "cryptogenic" because the cause is unknown. Aim: To study clinical and radiological spectrum of cases reported as COP. Materials and Methods: This is an observational study including secondary data analysis. The medical records, clinical and radiological profiles of COP patients, visiting Dr. Hedgewar Hospital, Aurangabad (2016-2019) were analyzed. Result: The Study included 25 cases. The urban: rural ratio was 14:11. Male: Female ratio was 14:11. The presenting symptoms were mainly Progressive dyspnoea (72%) and Dry cough (68%). Co-morbidities were observed in 72% patients and 28% patients required assisted ventilation. The radiological features were bilateral patchy opacities in 36%, unilateral consolidation in 24%, reticulo-nodular opacities in 8% patients. 32% of Chest Xray were reported as normal. HRCT Lung showed Ground Glass Opacities in 44%, Sub pleural And Interstitial Thickening in 23%, Multiple Nodular Enhancements in 14%, Cystic Changes and Traction Bronchiectasis in 15% and Others (Crazy paving, cavitory changes) in 4% patients. Steroids were administered in 48% patients. The mortality was 20%. The survivors (80% patients) showed clinical improvement. Elderly population, co-morbidities, smoking and ventilator support were the high risk factors for the outcome. Conclusion: COP has varied clinico-radiological spectrum. A high index of suspicion will lead to proper diagnosis and management resulting in better outcome. The steroid therapy resulted in better outcome.
Hand, foot and mouth disease, which was once considered a disease of cattle, has been emerging as a common human childhood disease in the last few years but is rare in adults. It is a viral disease characterised by a brief febrile illness and typical vesicular rashes. In rare cases, patients may also develop neurological complications. This report describes a case of hand, foot and mouth disease, presented with typical clinical features in the central Indian region.
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