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Extended total arch replacement for acute type A aortic dissection could be justified in properly selected patients.

Integrated cerebral protective effect of antegrade selective cerebral perfusion and total arch replacement with an aortic arch branched graft could substantially reduce in-hospital mortality and postoperative neurologic dysfunction in patients with atherosclerotic arch aneurysms.

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Administration of IL-1ra attenuates spinal cord ischemic-reperfusion injury as evidenced by reducing both neuronal necrosis and apoptosis.