Background: Burns are among the most prevalent injuries in humans with high cost in health care and heavy prolonged or permanent physical, psychological and social consequences. Commercial antimicrobial creams and dressing agents are unsuccessful in healing deep burn wounds. Materials and Methods: A study was conducted to assess the impact of crude linseed oil (LSO) topical application on burn wounds healing in rabbits in comparison with untreated wounds (NAT) and those treated with Vaseline gel (VAG) and Cicatryl-Bio ointment (CBO). By the 28 th day post burning, skin biopsies were analyzed for histological and cytological lesions. The presence of various bioactive phytochemical groups in linseed was also screened. Results: Phytochemical screening has resulted in high concentrations of flavonoids and terpenoids, low amounts of catechic tannins and total absence of alkaloids and saponosides. All along the trial, the rate of wounds contraction was found to be significantly higher in burns treated with LSO which had also a significant shorter healing period (26±5.89 days) as compared to the other treatments. LSO healed wounds included less inflammatory cells, complete epithelium regeneration with a reduced thickness of the new formed dermis, discreet fibrosis, enhanced neo-vascularization, increased number of collagen fibers, fibroblasts and many myofibroblasts. Additionally, no adverse effects of LSO on cicatrization process were recorded. Conclusion: These findings prove the safety and efficaciousness of linseed oil topical application in the therapy of burn wounds.

Background: The therapeutic safety of herbal medicine is a major concern for consumers and users. After studying the effects of linseed on hair growth in rabbits, the turn is to evaluate its safety by the observation of some clinical, biological and anatomo-pathological aspects. Materials and Methods: A study was conducted during a period of three months on two groups of rabbits (control and test). Test group daily received feed supplemented with 3g of ground linseed while the control animals received the same feed without any additives. Weekly, rabbits were weighed and monthly blood samples were taken. By the end of the trial, liver and kidneys biopsies were analyzed for histological and cytological lesions. Results: There was no significant improvement in weight gain in the test group rabbits, in which biochemical parameters had differentially evolved with a decrease in their Glycemia and cholesterolemia. There were also no modifications in their serum hepatic and renal marker enzymes and their liver and kidneys exhibited noticeably normal histology without any anatomically detectable anomalies. Conclusion: These findings confirm that prolonged linseed ingestion in rabbits is safe.

Background: The therapeutic safety of herbal medicine is a major concern for consumers and users. After studying the effects of linseed on hair growth in rabbits, the turn is to evaluate its safety by the observation of some clinical, biological and anatomo-pathological aspects. Materials and Methods: A study was conducted during a period of three months on two groups of rabbits (control and test). Test group daily received feed supplemented with 3g of ground linseed while the control animals received the same feed without any additives. Weekly, rabbits were weighed and monthly blood samples were taken. By the end of the trial, liver and kidneys biopsies were analyzed for histological and cytological lesions. Results: There was no significant improvement in weight gain in the test group rabbits, in which biochemical parameters had differentially evolved with a decrease in their Glycemia and cholesterolemia. There were also no modifications in their serum hepatic and renal marker enzymes and their liver and kidneys exhibited noticeably normal histology without any anatomically detectable anomalies. Conclusion: These findings confirm that prolonged linseed ingestion in rabbits is safe.

Aim: This experiment was conducted to determine the effects of the incorporation of these two cereals on the zootechnical performances, the biochemical profile, the characteristics of the carcass and the consumable offal of chickens. Methods: 318 broiler chicks (day-old) were divided into 3 lots. In group "barley", maize was partially replaced by crushed barley during the three conventional rearing phases, they are 31%, 32% and 35% respectively. In "triticale group" ; the chickens here consumed a feed in which maize was partially substituted during the three phases, they are 31% at starting, 32% during growth and 35% during finishing, respectively. Results: The best weight growth was obtained in the group fed the "barley" ration, followed by the "triticale" ration. The lowest live weight was recorded with the "control. On the other hand, the results show that triticale supplementation in the diet does not change the carcass characteristics of the chickens: non-significant variation between the "control" and "triticale" groups (P>0.05). Conclusion: Barley proved to have a positive influence on production performance such as live weight and carcass yield when incorporated into the ration. Keywords : Barley, Triticale, Substitution, Performance, Biochimical profil.

Background: Natural additives supplementation in broiler feed is intended to produce organic meat and minimize the use of chemical drugs that have harmful effects on humans, animals, and the environment. Using locally available plants such as fenugreek and green anise is a much safer and inexpensive alternative Methods: 318 broiler chicks were randomly assigned to three different experimental groups: birds of the first group considered as the control group received an enrofloxacin-based antistress drug; birds of the second group received an aqueous extract of fenugreek; birds of the third group received an aqueous extract of aniseed. Both natural products were used in gradual levels according to the following dosages and duration of treatment:7 grams/liter of water during the period from day15 to day 21 of age; 14 grams/liter of water from day 22 to day 28 and 28 grams/liter of water from day 29 to day 35. For each group, the following zootechnical parameters and carcass characteristics were recorded: mortality rates; Feed Intake (FI), Feed Conversion Ratio (FCR); live weight at slaughter; carcass yield and the weights of the liver, gizzard, and abdominal fat. Findings: Fenugreek was found to have the lowest mortality rate (6,60%) compared to 9,34% for the "control" group and 8,41% for the "anise group. Both Fenugreek and aniseed aqueous extracts had similar results to the synthetic antistress on the zootechnical and carcass variables studied. There was no significant difference between the three experimental groups (p> 0,05). Novelty: Supplementation of fenugreek and anise aqueous extracts in broilers' drinking water has no adverse effect on their zootechnical performance or carcass characteristics. Both natural products could replace synthetic enrofloxacin-based antistress, allowing organic broiler production with reduced costs.

Background: This study was performed to evaluate the performance of low soybean meal diets in broiler chicks. Methods: A total of 330 broiler chicks were divided into three groups. Each group was treated with one type of diet (group 1=control [soybean], group 2=crushed peas, and group 3=faba bean). The proportion of crude protein (CP) for the control group was 20.45% as a starter and 19.75% to 17.66% as a grower and finisher. The CP values for group 2 were 17.45% as a starter and 16.95% to 15.46% as a grower and finisher. While chicks of group 3 received 17.75% CP as a starter and 17.23% to 15.68% CP as grower and finisher. Data obtained were expressed as mean±SEM. The results obtained were analyzed using the ANOVA Test, by Minitab 2015 statistical analysis software. P-value < 0.05 was considered as significant. Results: Significantly (p<0.05) higher weight gain was obtained in the faba bean group (2744.72 g ±217) than control (2430.50 g ±593.8). No significant difference was noticed in the consumption of different diets. The carcass yield of control (70.10%) and faba beans (70.32%) groups were comparable. Concerning the biochemical parameters, we found that the partial change of soybean did not affect the biochemical profile, except for the significant variation of blood sugar, cholesterol, and triglycerides between the control and group 2 (p<0.05). Conclusion: Faba beans as a locally available source of protein could be a potential alternative to substitute soybean meal in the broiler diet.