Introduction. Acute pediatric poisoning has become an increasingly important medical emergency. This study was aimed at determining characteristics of acute poisoning in children and adolescents hospitalized at the Institute of Child and Youth Health Care of Vojvodina from 2015 to 2017. Material and Methods. Data were collected from medical records of all patients hospitalized for suspected acute intoxication at the Institute of Child and Youth Health Care of Vojvodina during the observed time. Results. This study included 519 patients hospitalized for suspected exposure to toxic substances. There were 49% male and 51% female patients. The intoxications had no seasonal features. The toxic substances were commonly taken orally. Medications were the most frequent cause of all poisonings, among which the most commonly reported were drugs for central nervous system disorders. Medications were the most frequent cause of poisoning in children and adolescents, as well as in children up to 10 years of age. In adolescents, the most prevalent cause of intoxication was alcohol abuse. Poisoning with suicidal intent and intentional self-poisoning without suicidal attempt were considerably more frequent in girls than in boys. There were no fatalities. Conclusion. It is of great importance to be familiar with the characteristics and circumstances of acute poisoning to plan and implement adequate preventive measures. SažetakUvod. Akutna trovanja predstavljaju jedno od čestih urgentnih stanja u pedijatriji. Cilj ovog istraživanja bio je da se odrede karakterisike akutnih trovanja kod pacijenata hospitalizovanih u Institutu za zdravstvenu zaštitu dece i omladine Vojvodine u periodu od 2015. do 2017. godine. Materijal i metode. Podaci za istraživanje prikupljeni su iz medicinske dokumentacije pacijenata koji su zbog sumnje na akutnu intoksikaciju ksenobioticima bili hospitalizovani u Institutu za zdravsvenu zaštitu dece i omladine Vojvodine tokom posmatranog perioda. Rezultati. Ovom studijom obuhvaćeno je 519 pacijenata koji su hospitalizovani zbog izloženosti toksičnim materijama. Bilo je 49% pacijenata muškog i 51% pacijenata ženskog pola. Učestalost trovanja ni je imala se-Učestalost trovanja nije imala sezonski karakter. Dominantni put unosa ksenobiotika je peroralni. Najčešći etiološki činilac ukupnih trovanja su lekovi, među kojima su najčešći uzročnici trovanja bili lekovi za lečenje bolesti centralnog nervnog sistema. Najčešći uzročnik trovanja kod dece i adolescenata su lekovi, kao i kod dece uzrasta do 10 godina. Kod adolescenata najčešći uzrok trovanja je alkohol, unet u svrhu uživanja, koji su više konzumirali mladići nego devojke. Trovanja sa suicidalnom namerom i namerna samotrovanja bez suicidalne namere bila su značajno češća kod devojaka nego kod mladića. Nije bilo smrtnih slučajeva. Zaključak. Poznavanje karakteristika i okolnosti akutnih trovanja je značajno kako bi se mogle planirati i sprovoditi adekvatne preventivne mere. Ključne
Introduction/Objective. The proportion of live-born infants conceived with assisted reproductive technologies (ART) in some European countries reaches 6% and in Serbia over 1%. The aim of this study was to analyze characteristics and morbidity of prematurely born newborns conceived with ART. Methods. The study included 154 prematurely born newborns from pregnancies conceived with ART and 154 prematurely born newborns conceived naturally hospitalized at the Institute of Health Care of Children and Adolescents of Vojvodina. Participants from both groups were matched according to gestational age and date of birth. Results. Statistically significantly more newborns with very low birth weight have been in group of newborns conceived by ART in comparison to newborns conceived naturally (?2 test, p = 0.0002). Morbidity of newborns conceived with ART is not higher in comparison to newborns of the same gestational age conceived naturally. Bronchopulmonary dysplasia, occurred more frequently in children from ART (?2 test, p = 0.006) and retinopathy of prematurity, occurred more frequently in children spontaneously conceived. (?2 test, p = 0.047). There was no difference in the frequency of birth defects, genetic syndromes and inborn errors of metabolism between two groups. Conclusion. Lower birth weight and intrauterine growth restriction are potential risk factors for worse postnatal outcome in newborns from pregnancies conceived with ART.
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