Highlights
This mini-review provides a thorough overview of current buccal/oral lyophilizates.
The mini-review discusses material and process parameters using the quality by design (QbD) approach.
This study covers trends in experimental buccal/oral formulations.
It relates drug and dosage form limitations to aid future developments.
It shows buccal/oral lyophilizates as safe and effective prominent drug delivery systems.
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