Among 19,864 infants born in Trondheim between 1 May 1969 and 31 December 1974 instability of the hip joint was diagnosed in 378 (19.03 per thousand live-born). All infants were treated with Frejka cushion splint, usually for 3 months. In spite of this early treatment, 31 infants (8.2 per cent) developed subsequent signs of CDH. In 20 children the diagnosis of CDH was based solely on radiological criteria, while 11 children also displayed clinical abnormalities, most often restricted abduction of the hip joint. The prenatal and perinatal condition of the 31 children, with persistent signs of CDH in spite of early treatment, was compared with that of the 347 children who showed no obvious signs of CDH. The former group of patients had a relatively high frequency of hip abnormalities in their families, and an increased frequency of breech presentation at birth, concomitant foot deformities and instability of the hip joint also on the eight day after birth. It is suggested that infants with unsatisfactory results from the early treatment of unstable hips constitute a separate clinical entity and an especially severe form of CDH.
When injected intravenously a t one time, Evans blue dye appears in a systemic artery along a rising and falling curve ( Fig. 1) of concentrations C, -C,, from which the cardiac output Vmin may be calculated.The formula is based upon a statical equation for homogeneous solutions as follows:(1) F = c . v in which F = quantity of dye in ml, C = dye-concentration in ml per liter and V = quantity of liquid mixed with the dye.Put in a dynamical equation one gets:(2) F = C,, * T -V,,,, with C, = mean concentration of the dye in flow, T = the time during which the dye is passing by, in seconds and V,,, = the volume per second.Thence one gets the second-volume
Summary
Total serum protein content was determined in the cord blood of 79 premature infants. There was a tendecy for the serum protein values to rise with the birth weight and gestational age. Boys had, on average, lower serum protein values than girls. 31 infants with serum protein content less than 5 g/100 ml were treated with albumin solution, 2 g per kg of body weight intravenously, on the first day of life. 27 infants, serving as controls, were not treated with albumin. The two groups showed the same frequency of “respiratory distress”. One infant died in connection with the administration of albumin.
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