Although intrauterine insemination (IUI) utilizing the husband's semen is widely used as a general fertility treatment, there are no clear policies determining the appropriate number of IUI cycles or a selection criteria for couples at our institution. In this study we investigated IUIs performed at our facilities in the past 3 years, and examined prognostic factors for pregnancy based on age, number of inseminations, and semen findings. A total of 341 patients who underwent 1,229 cycles of IUIs performed at our institution between January 2016 and December 2018 were included. The pregnancy rate was 6.2% per cycle and 21.1% per couple. In terms of age, we noted both men and women contributed to a decrease in the pregnancy rate with increasing age, but the effects of aging tended to be slightly less pronounced in men. The cumulative pregnancy rate for the number of times insemination was performed was approximately 50% by the second cycle, and 90% by the sixth. Assessment of semen analysis showed significant differences in motility and adjusted recovered sperm concentration (P<0.05).
Purpose: This study aimed to reveal the clinical significance of hysteroscopyin infertility treatment.
Methods:This retrospective, single-center, cohort study included 613 women of reproductive age who underwent hysteroscopy between April 2011 and March 2016. All women underwent a routine infertility work-up including transvaginal sonography, hysterosalpingography, and blood tests, and analysis of their husband's semen was performed. The Student t, Mann-Whitney, and Fisher exact tests were used to analyze the data.Results: Hysteroscopy as a routine work-up revealed an abnormal uterine cavity in 141 women (22.1%) and 114 endometrial polyps (80.9%). Endometrial polyps were more frequently observed in those with primary infertility (p<.005) and endometriosis (p<.005) than those without these conditions. Endometrial polyps were rarely observed in those with recurrent pregnancy loss (p<.05).
Conclusion:Hysteroscopy is recommended as a routine work-up before fertility treatment given the prevalence of endometrial polyps, especially for women with endometrioma, and their impacts on embryo implantation failure.
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