In this expository paper we give an overview of some statistical methods for the monitoring of social networks. We discuss the advantages and limitations of various methods as well as some relevant issues. One of our primary contributions is to give the relationships between network monitoring methods and monitoring methods in engineering statistics and public health surveillance. We encourage researchers in the industrial process monitoring area to work on developing and comparing the performance of social network monitoring methods. We also discuss some of the issues in social network monitoring and give a number of research ideas.
OBJECTIVESThis study evaluates the repeatability of brain perfusion using dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) with a variety of post-processing methods.METHODSThirty-two patients with newly diagnosed glioblastoma were recruited. On a 3-T MRI using a dual-echo, gradient-echo spin-echo DSC-MRI protocol, the patients were scanned twice 1 to 5 days apart. Perfusion maps including cerebral blood volume (CBV) and cerebral blood flow (CBF) were generated using two contrast agent leakage correction methods, along with testing normalization to reference tissue, and application of arterial input function (AIF). Repeatability of CBV and CBF within tumor regions and healthy tissues, identified by structural images, was assessed with intra-class correlation coefficients (ICCs) and repeatability coefficients (RCs). Coefficients of variation (CVs) were reported for selected methods.RESULTSCBV and CBF were highly repeatable within tumor with ICC values up to 0.97. However, both CBV and CBF showed lower ICCs for healthy cortical tissues (up to 0.83), healthy gray matter (up to 0.95), and healthy white matter (WM; up to 0.93). The values of CV ranged from 6% to 10% in tumor and 3% to 11% in healthy tissues. The values of RC relative to the mean value of measurement within healthy WM ranged from 22% to 42% in tumor and 7% to 43% in healthy tissues. These percentages show how much variation in perfusion parameter, relative to that in healthy WM, we expect to observe to consider it statistically significant. We also found that normalization improved repeatability, but AIF deconvolution did not.CONCLUSIONSDSC-MRI is highly repeatable in high-grade glioma patients.
Process monitoring and fault diagnosis using profile data remains an important and challenging problem in statistical process control (SPC). Although the analysis of profile data has been extensively studied in the SPC literature, the challenges associated with monitoring and diagnosis of multichannel (multiple) nonlinear profiles are yet to be addressed. Motivated by an application in multi-operation forging processes, we propose a new modeling, monitoring and diagnosis framework for phase-I analysis of multichannel profiles. The proposed framework is developed under the assumption that different profile channels have similar structure so that we can gain strength by borrowing information from all channels. The multi-dimensional functional principal component analysis is incorporated into change-point models to construct monitoring statistics. Simulation results show that the proposed approach has good performance in identifying change-points in various situations compared with some existing methods. The codes for implementing the proposed procedure are available in the supplementary material.
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