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Background: Babies with a birth weight of less than 2500 grams, irrespective of the period of their gestation are termed as Low Birth Weight (LBW) babies. Despite consistent efforts to improve the quality of maternal and child health, more than twenty million low birth-weight (LBW) babies are born every year throughout the world. Though, the health situation of Nepal has improved substantially over the years, the low birth-weight (LBW) rate is still high. The objective of this study was to assess the proportion of low birth weight and identify the associated factors for low birth weight in a live born infant among the institutionally delivered newborns. Methods:A hospital based cross sectional study was conducted in Obstetrics and Gynaecology ward of Bharatpur hospital, Bharatpur, from 17 th September to 4 th October , 2012. Altogether 480 respondents were taken and respondents were mothers who had delivered newborns in Bharatpur hospital.Results: A total of 480 births occurred during the study period, of which 480 met the study criteria. Among which 9.4% were low birth weight and 90.6% were normal birth weight .Overall mean birth weight was found to be 2.96 kg. Out of total 9.4% newborns were weighing less than 2.50 kg and mean birth weight 2.96kg. Conclusions:This study suggests that there were several factors interplaying which lead to LBW babies; which are age of mother at delivery,weight gain by mother during pregnancy, short, low body mass index and hyperemesis gravidarum was the strongest predictor in this study.

Species distribution models are a key component for understanding a species' potential occurrence, specifically in vastly undersampled landscapes. The current species distribution data for the Assamese macaque Macaca assamensis are outdated, but suggest a patchy distribution in moist broadleaved forests in South and Southeast Asia. Therefore, in this study, we used a species distribution model to explore the potential climatic niche of this species and assess its distribution and potential barriers in 12 South and Southeast Asian countries. We combined primary and secondary species occurrence records from different countries. We applied Classification and Regression Tree (CART), TreeNet (boosting), RandomForest (bagging) and Maximum Entropy (MaxEnt) machine-learning algorithms with elevation as well as 19 bioclimatic variables for the first ensemble predictions ever completed for this species. Our results suggested that the predicted distribution of the Assamese macaque is strongly associated with precipitation of warmest quarter (BIO18), temperature annual range (BIO7) and temperature seasonality (BIO4). Our prediction shows a continuous potential climatic niche of the species from east of the Kaligandaki River in Nepal to Lao People's Democratic Republic. There are also potential niche patches in Bhutan, Southeast China, Thailand and Cambodia, while Pakistan and Afghanistan have no potential niche for the species. We believe that our workflow presents a new conservationoriented open access research template to progress empirical primate conservation worldwide.

Nepal is one of the developing Countries in the South Asia. Early childhood is very important and the crucial period for the proper physical, mental and emotional development. Therefore child should be looked especially at this period. In Nepal, child below two years are suffering from malnutrition the most. The initiation of breastfeeding within one hour of birth has numerous nutritional and immunological benefits and has been found to reduce neonatal mortality. An improper feeding practice among young children par­ticularly 6-23 months is a major cause of malnutrition. Thus, the present study has been focused on feeding practices of fewer than two years children. The study was quantitative study. Main objective of the study was to know the feeding practices of under two years children after implementation of Baal Vita(Sprinkles) program in Raksirang VDC of Makwanpur district. Questionnaire was related to the Baal Vita(Sprinkles) program, Breast­feeding practices and Complimentary feeding practices. Altogether 132 mothers were taken for the study. The structured questionnaire was developed, pretested and used to collect the information. After the collection of data, it was analyzed by using SPSS 17.0.Also the data was presented in different tables to make it more clear and specific. Among 132 of the respondent, majority of the respondent were aged between21-25 years. 37.88% mothers were illiterate and only 1.52% had secondary level education. Some of the respondents were pregnant before the age 20 years. One of the mother was give birth to her child at age of 15 years.68.18% respondent had first Breastfed their child with in 1 hour of birth. Colostrum feeding was seen not good. This study found Still practice of squeezing colostrum. Current breastfeeding practice is seen good. About 88.64% of the respondent had started giving complementary food in correct time.

Introduction: Assessing anti-diabetic drug use patterns in hospitals is an important activity which helps to promote the rational use of drugs and may suggest measures to change prescribing habits for the better. This study aimed to find the use of combination therapy in diabetes mellitus patients attending the outpatient department of a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among 201 diabetes mellitus patients in the internal medicine department from 2 March 2022 to 30 June 2022 for a duration of four months after approval from the Institutional Review Committee (Protocol No: IRC-LMC-01/R-022). Diabetic patients prescribed at least one anti-diabetic drug in prescription forms were included. Socio-demographic profiles, clinical characteristics and anti-diabetic drug use pattern-related data were collected. Convenience sampling was used. Point estimate and 95% Confidence Interval were calculated. Results: Among 201 patients, 134 (66.66%) (60.14-73.18, 95% Confidence Interval) patients were given combination therapy. The most common combination therapy was metformin 500 mg and sitagliptin 50 mg. A total of 324 anti-diabetic drugs were used. The average number of drugs prescribed per patient was 1.6±0.7. The number of anti-diabetic drugs prescribed by generic name and from the national essential drugs list was 74 (22.83%) and 188 (58.02%) respectively. Biguanides were used in 176 (87.56%) patients. Conclusions: These findings were similar to some other studies conducted in similar settings. In most patients, combination drug therapy was more prevalent. Among combination therapy, two drug combinations were more prevalent.

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Complementary feeding for an infant refers to timely introduction of safe and nutritional foods in addition to breastfeeding i.e. clean and nutritionally rich additional foods introduced at about six months of infant age. Complementary feeding strategies encompass a wide variety of interventions designed to improve not only the quality and quantity of these foods but also improve the feeding behaviors. The objective of the study is to assess the factors affecting complementary feeding practices among mothers in Mangalpur, Chitwan. A cross sectional study was carried out to find out the factors affecting complimentary feeding practices among mothers of under two years children in Darai and Kumal Communities in Mangalpur, Chitwan. Altogether 84 respondents were included in this study. Data analysis was done by descriptive statistics and Inferential statistics and those data was analyzed by using the software SPSS (version 20.0). The percentage of Knowledge on complimentary feeding was found as 96.40 and correct practice was 73.80% in the study area. In this study, more than half (58.3%) of the respondent had first child at the age of nineteen or more. 86.90 % of the respondents had knowledge of complementary food and mostly (87.70) practiced lito as complimentary food. Almost all (98.80%) mothers had the knowledge of sarbottam pitho and 79.50% had correct knowledge of preparation. Complementary feeding was practiced correctly by 73.80% mothers.