Sickle cell disease (SCD) is an inherited haemoglobinopathy that may present acutely as stroke, vaso-occlusive crisis or acute chest syndrome. Acute conditions require prompt diagnosis and intensive management to prevent morbidity and mortality. Here, we present a case of sickle cell anemia treated with therapeutic red cell exchange that manifested as acute chest syndrome. A 26 year old male who had history of high-grade intermittent fever and cough with expectoration was diagnosed as pneumonia and put on antibiotics. Peripheral smear showed sickle cells and HPLC showed HbS of 67%. we made a diagnosis of sickle cell anemia with acute chest syndrome. We treated the patient with therapeutic red cell exchange following which HbS reduced to 24% from the initial 67%. We observed significant clinical improvement suggesting red cell exchange as a useful therapeutic option for acute sickle cell anaemia.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.