Azo compounds are a very unique class of chemical compounds, drawing
considerations in scientific research. Azo compounds are studied as class of organic colorants
which have at least a conjugated chromophore azo (-N=N-) group in fusion with one or more
aromatic or heterocyclic ring system. Benzimidazole derivatives are privileged intermediates
for the development of molecules of pharmaceutical or biological interest. Benzimidazole
derivatives have gathered wide applications in diverse therapeutic areas such as antiulcer,
anticancer agents, and anthelmintic species to name just a few. Although many azo derivatives
of benzimidazole nucleus has been reported in literature but only few of them have been
evaluated for their biological potencies. This review focuses primarily on those derivatives
which are evaluated as anticancer, antibacterial, antifungal, antitubercular, and other medicinal
agents. This review may be helpful for the investigators on the basis of substitution pattern on
the nucleus with an objective to assist medicinal chemists for developing an SAR on azo
benzimidazoles or similar compounds.
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