BackgroundTo study the corresponding strategies for controlling cancer in older adults aged 60 and above in China, a comprehensive assessment of disease burden is required. Therefore, we will introduce the cancer epidemiological characteristics of older adults in China over a recent 12 year period.MethodsThe age-period-cohort model was constructed using the cancer incidence data from the Chinese Cancer Registry Annual Report published in 2008–2019. The annual change percentage (APC) was estimated by log-linear regression to reflect the time trend. The data from the GLOBOCAN 2020 database was selected for worldwide comparative analysis.ResultsThe cancer incidence in older adults aged 60 and above in China showed a decreasing trend (APC = −0.73%, P = 0.009). The urban/rural ratio of cancer incidence increased from 0.94 to 1.07 (t = 3.52, P < 0.05), while the sex ratio (male/female) showed a significant decreasing trend only in rural areas (t = −6.77, P < 0.05), and the ratio decreased from 2.02 to 1.72. The results of the age-period-cohort model showed that the cancer incidence increased with age in both males and females, urban and rural areas. The RR of period effect increased from 2005 to 2010, then decreased from 2010 to 2015, and the downward trend was more obvious. The RR of the later-born cohort was lower than that of the earlier-born cohort in rural areas. Lung, gastric, colorectal, esophageal, liver, and breast cancers were common cancers in Chinese older adults. Lung cancer incidence ranked first in males, and it decreased with time in the 75–79 and 80–84 age groups (APC75 − 79 = −1.10%, APC80 − 84 = −0.88%, all P < 0.05). Breast cancer incidence ranked first among female in the 60–64 age group and showed an increasing trend (APC60 − 64 = 1.52%, P < 0.05).ConclusionsThe cancer incidence in Chinese older adults aged 60 and above showed a decreasing trend, but it was still at a relatively high level. The key targets of prevention and treatment should be males, urban areas, younger people, older adults aged 60–69, lung, gastrointestinal, and breast cancers in the future.
Background As populations age, cancer burden becomes increasingly conspicuous. This study quantified the cancer burden of the elderly (≥ 60 years) in China, based on the China Cancer Registry Annual Report to provide epidemiological evidence for cancer prevention and control. Methods Data on cancer cases and deaths among the elderly aged ≥ 60 years were collected from the China Cancer Registry Annual Report, 2008–2019. Potential years of life lost (PYLL) and disability-adjusted life years (DALY) were calculated to analyze fatalities and the non-fatal burden. The time trend was analyzed using the Joinpoint model. Results From 2005 to 2016, the PYLL rate of cancer in the elderly was stable between 45.34‰ and 47.62‰, but the DALY rate for cancer decreased at an average annual rate of 1.18% (95% CI: 0.84–1.52%). The non-fatal cancer burden in the rural elderly was higher than that of the urban elderly. Lung, gastric, liver, esophageal, and colorectal cancers were the main cancers causing the cancer burden in the elderly, and accounted for 74.3% of DALYs. The DALY rate of lung cancer in females in the 60–64 age group increased (annual percentage change [APC] = 1.14%, 95% CI: 0.10–1.82%). Female breast cancer was one of the top five cancers in the 60–64 age group, with DALY rates that also increased (APC = 2.17%, 95% CI: 1.35–3.01%). With increasing age, the burden of liver cancer decreased, while that of colorectal cancer rose. Conclusions From 2005 to 2016, the cancer burden in the elderly in China decreased, mainly reflected in the non-fatal burden. Female breast and liver cancer were a more serious burden in the younger elderly, while colorectal cancer burden was mainly observed in the older elderly.
Objective To explore the epidemiological characteristics and mortality trends of cancer in the older adults in China from 2005 to 2016 and to provide strategies for the prevention and treatment of cancer. Methods Stratified analysis was conducted on the cancer mortality data of the older adults aged ≥ 60 years in China, which were selected from the Chinese Cancer Registry Annual Report and GLOBOCAN 2020 database. The Joinpoint regression model was used to estimate mortality trends. The age-period-cohort model was used to explore the effects of age. Results 1. Cancer mortality in the older adults in China showed a decreasing trend from 2005 to 2016 (APC=-1.23%, P < 0.001). 2. Cancer mortality in the older adults in rural areas was higher than that in urban areas from 2005 to 2016, but the urban-rural difference gradually narrowed as the urban-rural ratio was risen from 0.79 in 2005 to 1.01 in 2016 (t = 4.32, P < 0.01). 3. The cancer mortality in the older adults in older women and rural areas showed a decreasing trend (women: APC60-69=-1.08%, APC70-79=-1.85%, APC80-84=-0.83%; rural: APC60-69=-3.31%, APC70-79=-3.12%, APC80-84=-1.22%; all P < 0.05). Older adults born before 1935 had a higher risk of death. 4. Lung, stomach, liver, esophageal, and colorectal cancers were the five most dominant cancers in the older adults in China. Conclusion Cancer mortality in the older adults in China showed a decreasing trend between 2005 and 2016 but it was still higher than the world average. We recommend to focus on the early cancer detection in the older adult men and in rural areas.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.