In this work, the design and implementation of a low power ternary full adder are presented in CMOS technology. In a ternary full adder design, the basic building blocks, the positive ternary inverter (PTI) and negative ternary inverter (NTI) are developed using a CMOS inverter and pass transistors. In designs of PTI and NTI, W/L ratios of transistors have been varied for their optimum performance. The ternary full adder and its building blocks have been simulated with SPICE 2G.6 using the MOSIS model parameters. The rise and fall times of PTI show an improvement by a factor of 14 and 4, respectively, and that of the NTI by a factor of nearly 4 and 17, respectively over that of earlier designs implemented in depletion-enhancement CMOS (DECMOS) technology. The noise margins improve by a factor of nearly 2 in PTI and NTI, respectively.The ternary full adder has been fabricated in MOSIS two micron n-well CMOS technology. The full adder and its building blocks, NTI and PTI have been tested experimentally for static and dynamic performance, compared with the SPICE simulated behavior, and close agreement is observed.The ternary-valued logic circuits designed in the present work which do not use depletion mode MOSFETS perform better than that implemented earlier in DECMOS technology. The present design is fully compatible with the current CMOS technology, uses fewer components and dissipates power in the microwatt range.
In the present study, we report the design and eco‐benign synthesis of new class of carbazolyl‐1,4‐dihydropyridine (1,4‐CDHP) and carbazolyl‐1,8‐dioxodecahydroacridine (CAD) derivatives via a three‐component coupling reaction of substituted carbazole aldehydes, ethyl acetoacetate/dimedone, and ammonium acetate under solvent‐free conditions at 112°C to 115°C. We also report an efficient one‐pot synthesis of new class of carbazolyl polyhydroquinoline (CPQ) derivatives via a four‐component coupling reaction of substituted ethyl acetoacetate, dimedone, ammonium acetate, and carbazole aldehydes in acetonitrile/water medium (3:1) at 73°C to 75°C in moderate yields. All the products were thoroughly characterized by 1H NMR, 13C NMR, Fourier transform infrared (FTIR), mass spectral, and CHN analysis. The synthesized heterocyclic compounds were evaluated for their in vitro antibacterial activity against pathogenic strains of both Gram‐negative and Gram‐positive bacteria. Minimum inhibitory concentration (MIC) of the active compounds was evaluated by macrodilution method. The CPQ derivative (8a) displayed superior antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi with the MIC values of 16.0 to 32.0 μg/mL in comparison with the reference drug. The mechanism of antibacterial action of the CPQ derivatives was investigated via scanning electron microscope (SEM) studies. The molecular docking studies indicate that the CPQ derivative (8a) binds to the cell wall protein of E coli and P aeruginosa by formation of hydrogen bonds with amino acid residues (TYR328 and GLU249) of the bacterial cell wall protein. The 1,4‐CDHP, CAD, and CPQ derivatives were either noncytotoxic or exhibited minimal cytotoxicity towards human mononuclear cells from peripheral blood. All the products were evaluated for Lipinski rule of five (RO5) and were found to have good oral bioavailability.
An improved Biginelli protocol for the efficient synthesis of a new class of carbazolyl dihydropyrimidinones mediated by CdS thin film nanoparticles deposited on the inner walls of a glass reactor as a recyclable, heterogeneous catalyst.
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