SUMMARY : Studies conducted by us have revealed that sensitized mesenteric lymph node (MLN) cells from donors, when put into tissue culture system, proceed to form antibody in vitro. The antibody produced by these cells was studied by the bacterial adherence phenomenon (BAP) and antibody hemolytic plaque (AHPT) techniques and it is estimated that about 40 % of these MLN cells are capable of producing antibody in vitro.The viability of MLN cells is essential for this antibody synthesis.The BAP and AHPT activity are present only in MLN cell cultures in immunized donors.The activity appears to be that of specific antibody which has been formed by these immunologically competent MLN cells during the in vitro incubation.

No abstract