Objective: The aim of this study is to investigate the presence of dissociative symptoms and whether they are related to childhood trauma and obsessive--compulsive symptoms in bipolar disorder type II (BD-II). Methods: Thirty-three euthymic patients (HDRS<8, YMRS<5) and 50 healthy subjects were evaluated by SCID-I and SCID-NP. We excluded all first and second-axis comorbidities. All patients and healthy subjects were examined with the Dissociative Experiences Scale (DES), Childhood Trauma Questionnaire (CTQ-53), and Yale-Brown Obsessive-Compulsive Disorder scale (Y-BOCS). Results: In pairwise comparisons between the BD-II and control groups, the total CTQ, emotional abuse, emotional neglect, DES, and total Y-BOCS scores in the BD-II group were significantly higher than those in the control group (p < 0.05). There were five cases with DES scores over 30 (15.2%) and one case (2%) in the control group. DES was weakly correlated with total CTQ and Y-BOCS in patients diagnosed with BD-II (r = 0.278, p < 0.05 and r = 0.217, p < 0.05, respectively). While there was no correlation between total CTQ and Y-BOCS, the CTQ sexual abuse subscale was found to be related to Y-BOCS (r = 0.330, p < 0.05). Discussion: These results suggest that there is a relation between childhood traumas and obsessive-compulsive symptoms, or that dissociative symptoms are more associated with anxiety than obsessive symptoms, which prevents the increase of obsessive-compulsive symptoms in BD-II.Eryilmaz G et al. / Arch Clin Psychiatry. 2015;42(2):38-40
Objectives
Skin picking disorder (SPD) falls into the category of “obsessive-compulsive disorder and related disorders” in the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition). Repetitive transcranial magnetic stimulation (rTMS) treatment has been reported to be a promising therapy in obsessive-compulsive disorder–related disorders. The purpose of this study was to demonstrate the efficacy of rTMS treatment in patients with SPD.
Methods
Fifteen patients with SPD were assigned to receive 3 weeks' treatment with either active (n = 8) or sham rTMS targeting the pre–supplementary motor area. Patients were evaluated using the Beck Depression Inventory, Beck Anxiety Inventory, Skin Picking Impact Scale, and the Yale-Brown Obsessive Compulsive Scale Modified for Neurotic Excoriation. Response to treatment was defined as a ≥35% decrease on Yale-Brown Obsessive Compulsive Scale modified for Neurotic Excoriation.
Results
Treatment response was achieved in 62.5% of patients (5/8) in the active group and 33.3% of patients (2/6) in the sham group. However, there were no significant differences between the groups in terms of primary and secondary outcomes.
Conclusions
In this exploratory study, active rTMS could not be demonstrated to be superior over sham in treatment of SPD. The results of this study indicate the need for further rTMS studies to be conducted with larger sample sizes and subtypes of SPD.
ÖZET:Kırkdört yıllık iyileşme dönemi sonrası tekrarlayan mani: Bir olgu sunumu İki uçlu bozukluk, geçen yıllar ve artan dönem sayısı ile aradaki iyilik dönemlerinin ve hecmeler arası sürenin kısaldığına inanılan ilerleyici bir hastalıktır. Bununla birlikte birçok iki uçlu hastada hastalık istikrasız ve tahmin edilemez bir seyir izlemektedir. Bazı iki uçlu hastalar koruyucu tedavi almamalarına karşın yeni bir atak yaşamakta ya da dönemler arası süre onlarca yılı bulabilmektedir. Biz bu yazıda, koruyucu tedavi olmaksızın 44 yıl düzelmede olan bir mani vakasını sunmayı ve koruyucu tedavinin gerekliliğini ve süresini tartışmayı amaçladık.
Anahtar sözcükler: iki uçlu bozukluk, mani, yineleme, koruma
Journal of Mood Disorders 2012;2(2):66-9 ABS TRACT:Recurrence of mania after fourtyfour year remission: a case report It is widely believed that bipolar disorder is typically a progressive condition, marked by shortening of stable mood periods and of inter-episode cycles over time and increasing number of episodes. However, in many bipolar patients an erratic and unpredictable course of illness may occur. Experienced clinicians are familiar with some patients, whom have not suffered from a relapse of illness for years despite lack of prophylactic treatment. In this report we present a case of mania with 44 years of remission without prophylactic treatment and discuss the preventive therapy in bipolar disorder.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.