We describe a trichoblastic carcinosarcoma on the forehead of a 65-year-old man. This is the fifth case of trichoblastic carcinosarcoma in the literature and the first to be reported from the USA. It was successfully treated with direct excision. Trichoblastic carcinosarcoma should be distinguished from epidermal carcinosarcoma. We believe trichoblastic carcinosarcoma is an authentic carcinosarcoma derived from multiple progenitor cells whereas epidermal carcinosarcomas are derived from a single progenitor cell that undergoes epithelial to mesenchymal transition, and are better considered as sarcomatoid carcinomas.
Laser triggered, megavolt, megampere gas switches are frequently utilized to synchronize multiple pulsed power driver modules for inertial-confinement fusion, isentropic compression, and radiation physics experiments. The device developed to synchronize the 36 modules of the refurbished Z accelerator at Sandia National Laboratories is a 5.4 MV, 700 kA, sulfur-hexafluoride (SF 6 ) filled, laser triggered gas switch. At this operating level, switch jitter is 5 ns, the prefire rate is less than 0.1%, the average optic lifetime is greater than 200 shots, and the flashover rate is less than 1%. Over 1000 shots on a single-module test facility were conducted while iterating several potential design improvements, including utilizing low-erosion electrode material, varying SF 6 pressure, and modifying internal switch geometry all while keeping the basic switch architecture and footprint constant. Results of this development effort are presented herein.
The Z pulsed power driver at Sandia National Laboratories is used to develop high energy density z-pinch x-ray sources for inertial confinement fusion research and radiation effects testing, and drive megabar pressures in material samples for equation of state studies. The pulsed power system is in the process of being replaced, improving reliability and increasing energy delivered to the load.The upgraded pulsed power system will deliver more than nine megajoules of forward wave energy in the first one hundred nanoseconds of its pulse. The system is comprised of thirty-six nominally identical modules, each producing a 3.3-terawatt pulse in 6Q water-insulated transmission lines. The peak forward-going voltage is about 5 MV. The pulse rise time is -75 ns; the full width at half maximum is -190 ns. The thirty-six modules are combined in parallel and drive twenty to twenty-five MA into the single load. In such a system, reliable insulation and precise switching are primary concerns. We will show key components of the system and results from a test module. We will also show performance results from the energy storage, triggering, and pulse-forming systems. We will also show the differing constraints of power flow from the 175 kA from each Marx generator, to currents in excess of 24 MA in the final feed to the load.
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