Purpose To construct a breast cancer bone-only metastasis (BCBM) risk and prognostic model for Asian females and provide a reference for treatment selection in breast cancer (BC) patients with bone-only metastasis (BM). Patients and Methods The data for newly diagnosed female patients of Asian Pacific Islander (API) ethnicity between 2010 and 2018 were obtained from the Surveillance, Epidemiology, and End Results database. A total of 16,972 patients were identified. Logistic regression analyses were used to establish a risk model for BCBM. Cox proportional hazards regression analyses were used to construct nomograms for the prognosis of BC and BCBM. Subsequently, the degree of discrimination of the nomogram was evaluated using the consistency index (C-index) and receiver operating curve. Results The main independent risk factors of BM in Asian females with BC were primary site surgery (p<0.0001), ER (p=0.0015), and T-stage (p=0.0046). The C-index values in the training and validation cohorts were 0.933 and 0.941, respectively. The main independent risk factors of the prognosis of BC were age (p<0.001), summary stage (p<0.001), and grade (p=0.002). The C-index values of 5-year overall survival (OS) in the training and validation cohorts were 0.823 and 0.804, respectively. The risk factors of the prognosis of Asian females with BCBM were subtype (p<0.001), histology (p<0.001), and grade (p=0.033). The C-index values of 5-year OS in the training and validation cohorts were 0.793 and 0.723, respectively. Conclusion Using population-based analysis, this study constructed a prediction model for the risk and prognosis of BM in Asian females with BC. Another newly constructed model was effective in predicting OS in BCBM patients. These models can help prevent skeletal-related events and weigh the risks and benefits of surgery for metastatic lesions in BCBM patients.
In the era of the experience economy, ‘consumption experience’ has become an important part of people’s daily life needs. In this study, we adopted the perspective of user experience quality evaluation and found problems through field research; then, we built the evaluation dimension of theme creative markets based on experience quality combined with expert interviews to design the questionnaire. First of all, through online and offline questionnaire analysis on the experiencers of some theme creative markets in Guangzhou, the main factors that affect the quality of the tourists’ experience was explored. Secondly, through the analysis of the three dimensions of environment, activity, and service of some of the theme creative markets in Guangzhou, it was found that tourists have the highest score on the market activity and the lowest score on the market environment. Thirdly, through field observation and interviews with some experiencers, the reason for the low experience score was discovered. Finally, the corresponding design strategies were proposed for the environment, activities, and services, with a view to providing a reference for the improvement of the quality of the tourists’ experience and the improvement of the design of the theme creative markets.
Street commerce is the basic unit of urban structure and an important part of people’s life. With the continuous advancement of online commerce, people’s consumption habits and consumption patterns have begun to change. (1) Background: During the epidemic, the global business environment changed dramatically, and traditional street business has also been hit hard, leaving a lot of idle space. The question is how to solve the problem of activating the commercial street space after its decay, and realize its sustainable development. (2) Methods: This paper takes the commercial space of Nonglin Street as the object, constructs the relevant factors affecting the commercial space of the street by using the theory of scenes, and collects the data by means of a field investigation and questionnaire. According to a weight analysis and satisfaction analysis, the advantages and disadvantages of the commerce in Nonglin Street are understood. (3) Results: The importance of the three variables of the appearance, comfort and diversity of the commercial space in Nonglin Street is very high and the satisfaction is low. (4) Conclusions: Nonglin Street need to increase diversified forms of business, open block space, integrate regional cultural symbols, and improve the management model of street commerce.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.